Latvia

Latvia addresses Alzheimer’s disease through its state-funded healthcare system, where structured clinical pathways guide patients from primary care to specialist neurological evaluations. However, the country operates without a dedicated national dementia strategy, leading to long diagnostic wait times and a heavy reliance on municipal or private social care that is often unevenly distributed. To combat these systemic gaps, innovative, community-led initiatives are emerging; notably, “Sāras dārzs” (Sarah’s Garden) in Riga is Latvia’s first multisensory day center designed to provide dementia-adapted activities and vital caregiver respite. At the research and policy level, Latvia is actively working to modernise its approach by participating in JADE Health, a major EU-funded collaboration led locally by Riga Stradiņš University. This initiative aims to improve early detection, public health literacy, and person-centered care across the country.

Overall
AD Rating
Diagnostic Pathway
Latvia maintains formal clinical guidelines and patient pathway protocols directing individuals from general practitioners to specialised neurologists for standard cognitive screens and structural neuroimaging, though public system wait times are severely bottlenecked and advanced biomarkers remain largely experimental.
Specialized Care
Core anti-dementia medications and regular specialist visits are heavily subsidised by the National Health Service with capped patient copayments, but Latvia lacks a state-funded network of specialized memory clinics or dedicated gerontopsychiatric daytime hospitals.
Caregiver Support
The Latvian government provides no direct Alzheimer's-specific caregiver allowances, leaving municipalities and non-governmental entities to independently develop specialised respite options like Riga's multisensory day center, "Sarah's Garden."
National Policies
Latvia currently operates without a dedicated national dementia strategy, forcing Alzheimer's care to be managed through general health pathways rather than a centralised, disease-specific policy framework.
Access to ATT-s
Multiple therapies approved; limited or no reimbursement.
Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Highlights

Health system
Universal, Government-Funded (Mixed Provision)
ADI member association(s)
National dementia plan
Dementia plan funding
No plan
Dementia prevalence rate
1688
Dementia incidence rate
292
*per 100k Population
Prevalence Rate (per 100,000): 
This measures the total number of existing cases (both old and new) in a population at a specific point in time, divided by the total population and multiplied by 100,000. It tells you the overall "burden" or how widespread a condition is at that moment.
Incidence Rate (per 100,000): 
This measures the number of new cases that develop in a population over a specific period (usually one year), divided by the population at risk and multiplied by 100,000. This tells you the "speed" or risk of contracting the condition.

Population

1,833,405

Median age

43.8

Health expenditure (% of GDP)

7.60

Diagnosis

Latvia has established national guidelines and patient pathways for Alzheimer’s disease, beginning with family-doctor assessment and referral to a neurologist or psychiatrist. Cognitive assessment may include MMSE, MoCA and other standardised screening tools, alongside laboratory tests and CT or MRI. CT is routinely used to exclude structural and vascular causes, while MRI is preferred for assessing Alzheimer’s-related brain atrophy. Genetic testing and routine biomarker assessment are not part of standard clinical practice and remain largely confined to research. Long waiting times are a significant barrier, with state-funded specialist consultations and neuroimaging potentially taking several months to over a year, particularly in regional clinics. Most diagnostic costs are publicly funded through the NVD, with regulated co-payments capped at €570 annually.

Diagnosis pathway

Alzheimer’s diagnosis in Latvia follows national clinical guidance, beginning with family doctors who identify cognitive decline and refer patients for specialist assessment. Neurologists and psychiatrists, primarily in regional and tertiary hospitals, conduct cognitive evaluation using tools such as MMSE and MoCA, alongside blood tests and CT or MRI to exclude alternative causes. Family doctors generally do not establish the final diagnosis. CSF biomarker testing and PET remain outside routine publicly funded pathways, with access largely limited to specialised research facilities or privately funded services.

Latvia has established standardised clinical practice recommendations under the “Clinical Guideline for Alzheimer’s Disease, Vascular Dementia, Lewy-Body Dementia, and Frontotemporal Dementia” alongside patient pathway protocols (Pacientu ceļi) published by the Center for Disease Prevention and Control (Slimību profilakses un kontroles centrs). The formal diagnosis pathway begins in primary care, where patients or family members consult a general practitioner, locally termed a family doctor (ģimenes ārsts). Family doctors conduct initial physical evaluations, take patient histories, and identify primary symptoms of cognitive decline. However, due to time constraints in primary practice and limited specialized neurodegenerative training, family doctors do not provide a final diagnosis; instead, they serve as triaging providers who issue formal state referrals to specialised medical professionals.

Specialist evaluations for Alzheimer’s disease are conducted primarily by neurologists and psychiatrists operating within regional clinical hospitals or tertiary institutions, such as Paula Stradiņš Clinical University Hospital and Riga Eastern Clinical University Hospital (Gaiļezers). During specialist consultations, clinicians administer validated cognitive screening batteries, most notably the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), to measure executive function, orientation, and memory retention. Specialists order routine laboratory blood tests to rule out reversible metabolic conditions, such as thyroid dysfunction or vitamin deficiencies. Structural neuroimaging—specifically Computed Tomography (CT) or Magnetic Resonance Imaging (MRI)—is routinely performed to evaluate brain tissue loss, detect cerebral atrophy, and exclude vascular lesions or space-occupying intracranial masses. Advanced biomarker evaluations, including cerebrospinal fluid testing or positron emission tomography (PET) imaging, are not part of routine state-funded diagnostic pathways and remain limited to specialised university research units or out-of-pocket private care.

Wait times

Long wait time (expected)

Wait times for state-funded diagnostic services present a substantial challenge within Latvia’s public healthcare system. Patients seeking a state-financed appointment with a neurologist or state-funded diagnostic neuroimaging encounter waiting periods ranging from several months to over a year in regional clinics.

Diagnosis cost

Mostly or fully covered

Latvia’s state healthcare system covers most Alzheimer’s diagnostic costs for eligible patients through the National Health Service (NVD), with patients paying regulated contributions. Family-doctor visits cost €1–2, specialist consultations €4, CT €14–21 and MRI €28–35, depending on contrast use; MRI requires specialist referral for state funding. Patient contributions are capped at €570 per calendar year, after which qualifying services are exempt from further charges.

For patients entitled to state-funded healthcare in Latvia, the government bears most of the formal cost of diagnosing Alzheimer’s disease through the state healthcare system. The Latvian National Health Service (Nacionālais veselības dienests, NVD) states that the state budget covers family-doctor care, specialist care and diagnostic examinations when medically indicated and obtained through providers contracted to provide state-funded services. The patient normally pays only the prescribed contribution rather than the full cost, though it’s worth noting that overall out-of-pocket payments by patients still account for approximately 27% of total health expenditure in the country.

There are small co-payments for doctor visits. According to the latest Latvian NVD schedule, a family-doctor visit costs the patient €2 for people under 65 and €1 for people aged 65 or over, while a state-funded specialist consultation carries a €4 patient contribution. The remainder is financed by the state. The NVD lists patient contributions of €14 for CT without contrast and €21 with contrast, and €28 for MRI without contrast and €35 with contrast. MRI requires a referral from a specialist for it to be state-funded. Patient contributions for state-funded services are capped at €570 per calendar year, after which the patient can obtain exemption from further qualifying contributions for the remainder of that year.

Cognitive tests

Available

Under national clinical guidelines, GPs utilise standardised instruments including the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), or combination screenings such as the 5-Word Recall Test and the Clock Drawing Test.

Imaging tests

Commonly used

Structural neuroimaging is available and integrated into Latvia’s care pathway. Computed Tomography (CT) scans are routinely performed across regional hospitals to rule out vascular pathology, structural space-occupying lesions, or normal pressure hydrocephalus. Magnetic Resonance Imaging (MRI) is the preferred modality for evaluating hippocampal volume loss and medial temporal lobe atrophy characteristic of Alzheimer’s disease, with GPs and specialists able to order brain MRI within the diagnostic pathway.

Genetic tests

There is no evidence of genetic testing for Alzheimer’s disease availability within the standard clinical care in Latvia.

Biomarker tests

Rarely used

In Latvia, standard clinical practice does not include routine biomarker evaluation for Alzheimer’s disease, as its application is limited to academic research.

Cognitive Tests

Available

Under national clinical guidelines, GPs utilise standardised instruments including the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), or combination screenings such as the 5-Word Recall Test and the Clock Drawing Test.

Imaging Tests

Commonly used

Structural neuroimaging is available and integrated into Latvia’s care pathway. Computed Tomography (CT) scans are routinely performed across regional hospitals to rule out vascular pathology, structural space-occupying lesions, or normal pressure hydrocephalus. Magnetic Resonance Imaging (MRI) is the preferred modality for evaluating hippocampal volume loss and medial temporal lobe atrophy characteristic of Alzheimer’s disease, with GPs and specialists able to order brain MRI within the diagnostic pathway.

Genetic Tests

There is no evidence of genetic testing for Alzheimer’s disease availability within the standard clinical care in Latvia.

Biomarker Tests

Rarely used

In Latvia, standard clinical practice does not include routine biomarker evaluation for Alzheimer’s disease, as its application is limited to academic research.

Treatment & Care

Specialised dementia infrastructure remains limited in Latvia, without a publicly funded memory-clinic, neurological day-hospital, or gerontopsychiatric network. Neurologists and psychiatrists therefore provide most specialist care, while municipalities organise social services, producing uneven dementia-specific provision. National palliative care offers hospital and home-based multidisciplinary support and can include advanced dementia when eligibility criteria are met. Public healthcare funding covers Alzheimer’s treatment with patient copayments and medicine reimbursement according to national categories. Family caregivers receive no Alzheimer’s-specific financial benefit, although disability-related allowances and remunerated assistant services are available based on assessed needs. Home healthcare is similarly determined by chronic illness, mobility, and functional requirements.

Specialized facilities and services

Latvia lacks a state-funded network of specialised memory clinics, dementia day hospitals or gerontopsychiatric clinics, with specialist care mainly provided through outpatient neurology and psychiatry services and hospital departments. Municipalities provide home, day, respite and long-term social care, but dementia-specific provision varies geographically; Riga offers dedicated day-care services for people with dementia and mild cognitive impairment. State-funded palliative care is available through hospitals and multidisciplinary mobile teams, including home-based services. However, there is no dedicated dementia-specific palliative-care network.

Latvia currently has no state-funded network of specialised memory clinics, neurological dementia day hospitals or gerontopsychiatric clinics. This is stated explicitly in Latvia’s official 2025 clinical algorithm for dementia assessment and diagnosis: the specialised neurological day hospital and gerontopsychiatric clinic envisaged in the care pathway have not yet been established or included in the state-funded system. In practice, people with suspected or diagnosed dementia are assessed by neurologists or psychiatrists in outpatient services, with hospital neurology or psychiatry departments managing cases where necessary.

Latvia provides home care, day-care, respite and long-term social care through municipal social-service systems, but provision specifically designed for dementia is uneven. National legislation requires social care to be available according to assessed needs, including care at home and day-care services, but individual municipalities organise much of the provision. Riga specifically provides day-care services for people with dementia and has expanded eligibility to people with mild or moderate cognitive impairment, whereas comparable dementia-specific services are not consistently documented across all municipalities.

Latvia has strengthened palliative care through a state-funded system that includes hospital care and multidisciplinary mobile palliative-care teams providing care at home. Under the national Palliative Care Regulations, eligible adults with an expected survival of up to six months can receive home-based services that combine medical care with social care, technical aids and psychosocial support, following assessment by a hospital medical council. Palliative care is not restricted to cancer in the legislation, so a person with advanced dementia may qualify on the basis of palliative-care need and prognosis, although there is no separate dementia-specific palliative-care network.

Approved medication

Generic Name Trade Name Used for
Donepezil Aricept, Aricept ODT, Adlarity, Eranz, Memac, Alzepil, Davia, Donecept, Donep, Donepex, Donesyn, Dopezil, Yasnal, Memorit, Pezale, Redumas, Zolpezil, Namzaric* Donepezil is indicated for the symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Rivastigmine Exelon, Exelon Patch, Prometax, Rivastach, Nimvastid Symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Symptomatic treatment of mild to moderately severe dementia in patients with idiopathic Parkinson’s disease.
Galantamine Razadyne, Razadyne ER, Reminyl, Reminyl XL, Nivalin, Lycoremine, Galsya Galantamine is indicated for the symptomatic treatment of mild to moderately severe dementia of the Alzheimer type.
Memantine Namenda, Namenda XR, Ebixa, Memary, Axura, Akatinol, Maruxa, Nemdatine, Namzaric* Treatment of adult patients with moderate to severe Alzheimer’s disease.
Lecanemab Leqembi Lecanemab is indicated for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease in adult patients that are apolipoprotein E ε4 (ApoE ε4) heterozygotes or non-carriers.
Donanemab Kisunla Donanemab is indicated for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease (AD) in adult patients that are apolipoprotein Eε4 (ApoE ε4) heterozygotes or non-carriers.

*Namzaric = combination of Donepezil and Memantine

Treatment cost

Alzheimer’s treatment in Latvia is mainly state-funded through the National Health Service (NVD), although regulated patient co-payments apply. GP visits cost €1–€2 and specialist consultations €4, with qualifying healthcare co-payments capped at €570 annually. Medicines are reimbursed at 100%, 75% or 50% of the reference price, leaving patients to cover any unreimbursed amount or additional cost for more expensive alternatives.

Alzheimer’s treatment is financed mainly by the state through the National Health Service (Nacionālais veselības dienests, NVD), but it is not entirely free at the point of use. State-funded GP, specialist, diagnostic and other covered healthcare services generally involve fixed patient copayments—for example, €1–€2 for a GP visit (depending on age) and €4 for a specialist visit. These healthcare-service copayments are capped at €570 per calendar year, after which the patient can obtain exemption from further qualifying copayments; certain population groups are exempt altogether.

All medicines in Latvia are reimbursed according to the diagnosis and reimbursement category, generally at 100%, 75%, or 50% of the reimbursement/reference price; where reimbursement is less than 100%, or where a more expensive non-reference medicine is chosen, the patient/family pays the remaining amount.

Caregiver support

Latvia has no national financial allowance specifically for family caregivers of people with Alzheimer’s disease. Support is primarily based on the care recipient’s assessed disability and dependency, including disability benefits and publicly funded assistant services. State-funded home healthcare is also available to people with chronic illnesses and mobility limitations who cannot attend healthcare facilities, subject to medical eligibility. These measures are based on functional need rather than an Alzheimer’s diagnosis.

In Latvia, there is no national financial benefit specifically for family caregivers of people with Alzheimer’s disease. Latvia’s financial support is primarily linked to the care recipient’s formally assessed disability and dependency rather than to Alzheimer’s disease itself. The Ministry of Welfare provides disability-related allowances and publicly funded assistant services for eligible people with disabilities. Assistants are remunerated for the service they provide; in 2026, government funding provides hourly compensation generally around €5.72 – €6.03, depending on the month. However, this is not an Alzheimer’s disease-specific caregiver allowance.

State-funded healthcare at home is available to people with chronic illnesses who have mobility limitations and cannot attend a healthcare facility, subject to medical eligibility. This can be continued beyond the initial 30-day period where a family doctor determines that home healthcare remains necessary. Eligibility is based on health and functional needs rather than specifically on Alzheimer’s disease.

Policy

Latvia has no dedicated national dementia or Alzheimer’s disease strategy, and no upcoming or officially announced strategy has been identified. This represents a significant gap in the national policy framework. A systematic review found that Latvia’s clinical guideline does not explicitly address protection against discrimination, while a 2024 study of family caregivers identified personal stigma alongside guilt, insufficient social and professional support, financial difficulties and inadequate care. Limited formal support may reinforce the perception of dementia care as a private family responsibility, potentially increasing social isolation and limiting community participation for people with dementia.

National dementia plan

Latvia does not have a dedicated national dementia or Alzheimer’s disease strategy.

Upcoming plans

There are currently no upcoming or officially announced national strategies for Alzheimer’s disease or dementia.

Policy gaps

Legal barriers

A major institutional issue is the absence of a national dementia strategy. A systematic review of national dementia guidelines also found that Latvia’s clinical guideline did not explicitly include protection against discrimination, suggesting another policy-level gap relevant to stigma.

Cultural barriers

Dementia caregivers in Latvia face guilt, financial difficulties, inadequate support, and personal stigma. Limited formal provision may reinforce family-care expectations, increasing social isolation and reducing opportunities for people with dementia to participate in community life.

A 2024 study interviewed Latvian family caregivers, including carers of people with Alzheimer’s-type dementia, Parkinson’s dementia and other dementias. Caregivers described guilt, insufficient support from family and friends, financial difficulties, inadequate professional care and neglect of their own needs; importantly, the researchers explicitly identified coping with personal stigma as an issue within caregivers’ experiences. The lack of adequate formal support can reinforce this cultural problem: where dementia care is implicitly treated as a private family responsibility, families may become socially isolated and patients have fewer opportunities for ordinary community participation.

Research

Latvia’s State Agency of Medicines) is responsible for evaluating, authorising and overseeing clinical trials and medicines. The country has no separate public-facing national clinical-trial registry and authorised trials are registered through the CTIS. Latvia also participates in JADE Health, a €5.625 million EU-funded initiative running from January 2025 to December 2027, with approximately €114,018 allocated to Latvia. Led nationally by Riga Stradiņš University’s Institute of Public Health, with RAKUS as an associated partner, the project focuses on dementia prevention, earlier detection, care, health literacy and education.

Selected academic institutions

Riga East University Hospital Riga Stradiņš University University of Latvia

Clinical trials and registries

The State Agency of Medicines of Latvia (Zāļu valsts aģentūra) is the primary national institution responsible for evaluating, authorising, and overseeing all clinical trials and pharmaceuticals in the country. Latvia does not maintain its own separate, public-facing national registry for searching active clinical trials. All clinical trials authorised to take place in Latvia are registered and publicly tracked through the European Union’s Clinical Trials Information System (CTIS).

Selected innovative methods

Latvia participates in JADE Health (Joint Action addressing Dementia and Health), an EU-funded initiative running from January 2025 to December 2027 under the EU4Health programme. Riga Stradiņš University’s Institute of Public Health is the lead Latvian partner, with Riga East University Hospital (RAKUS) as an associated partner. The €5.625 million project, including approximately €114,018 allocated to Latvia, focuses on dementia prevention and health literacy, earlier detection, improved care and education for healthcare professionals, caregivers and families.

JADE Health (Joint Action addressing Dementia and Health) is a large EU-funded collaboration designed to improve how European health systems prevent, detect, treat and care for dementia and other neurological disorders. It runs from January 2025 to December 2027 under the EU4Health programme. Latvia participates through the Riga Stradiņš University Institute of Public Health as the lead Latvian partner and Riga East University Hospital (RAKUS) as an associated partner. Total project funding is €5.625 million, with approximately €114,018 allocated to Latvia. The project focuses on several connected areas: improving public understanding and health literacy around dementia; encouraging prevention and healthier behaviours; developing earlier detection and screening, particularly for people at higher risk; improving support and care for people living with dementia and other neurological conditions; and educating healthcare professionals, caregivers and families.

Support

Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Latvia’s dementia support is developing through Alzheimer Latvia, the Society Integration Foundation, and several Riga-based initiatives. A proposed support and competence centre will provide caregiver guidance and practical assistance, while Sarah’s Garden offers specialised day care, socialisation, and respite. The Dementia Café provides a stigma-free environment for affected families to connect and share experiences. Despite expanding community provision, Latvia currently has no standalone media outlet dedicated exclusively to dementia.

Selected national associations, patient family associations, NGOs:

Alzheimer Latvia

Selected initiatives

Latvia is developing community dementia support through several Riga-based initiatives. The city’s 2026 action plan proposes a dedicated centre providing consultations, caregiver training, information, and technological assistance. Sarah’s Garden, opened in 2026 as Latvia’s first multisensory dementia day centre, offers adapted activities, professional support, socialisation, and caregiver respite. The Dementia Café complements these services by providing an informal, stigma-free environment where people affected by dementia and their families can connect, exchange experiences, and participate socially.

Dementia Action Plan in Riga
In 2026, Riga developed an action plan for people with dementia and their relatives, noting that approximately one-third of people receiving municipal home-care services have dementia. The municipality is also planning its first dedicated support, technology and competence centre for people with dementia and their relatives, with proposed EU-supported funding of €300,000. The centre is intended to provide professional consultations, practical caregiver skills, information and technological support. This is a promising caregiver-focused development, but it is a municipal/project-based service rather than a national cash benefit.
Sarah’s Garden initiative
A major new initiative opened in January 2026: “Sāras dārzs” (Sarah’s Garden), described by Latvia’s Society Integration Foundation as the country’s first multisensory day centre specifically for people with dementia. Established by the Malteser Relief Service (Maltas Ordeņa palīdzības dienests) with public funding, the centre can accommodate approximately 15–20 people per day. Sarah’s Garden provides a safe social environment with dementia-adapted activities, professional support and opportunities for socialisation, while simultaneously providing respite for family caregivers.
Dementia Café
Dementia Café was launched by the Latvian Centre for Contemporary Art (LCCA) in Riga in 2022 alongside artist Anna Priedola's Dairy Diaries exhibition. The café was conceived as an informal, stigma-free setting where families affected by dementia could meet, exchange experiences and solutions, and participate socially together.

Dedicated media outlets

There are currently no dedicated, standalone media outlets that focus exclusively on Alzheimer’s disease or dementia in Latvia.

Understanding the terms

This section explains key terms used throughout the text to help readers better understand the exploration concepts.
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Contents

Understanding the Terms

Terms used throughout this website are explained below.
A

Amyloid-Targeting Therapies (ATT): A class of disease-modifying treatments, primarily monoclonal antibodies, designed to identify and remove amyloid-beta plaques from the brain to slow cognitive and functional decline in early-stage Alzheimer’s. Examples include Lecanemab and Donanemab.

Aphasia: A language disorder that affects a person’s ability to communicate, often seen early in Frontotemporal Dementia.

APOE ε4 Allele: A genetic variant of the Apolipoprotein E gene that is a major risk factor for late-onset Alzheimer’s disease; while not a causative gene, its presence increases the likelihood of developing the condition.

Acetylcholinesterase Inhibitors: A class of medications, including Donepezil, Rivastigmine, and Galantamine, used to treat cognitive symptoms by increasing levels of chemical messengers in the brain.

Advance Directives (DAT): Legal documents, such as Disposizioni Anticipate di Trattamento in Italy, that allow individuals to specify their future medical treatment and care preferences while they still have the capacity to do so.

Alzheimer’s Disease (AD): The most common cause of dementia, characterized by a progressive neurodegenerative decline caused by the accumulation of amyloid plaques and tau tangles in the brain.

Amyloid-beta Plaques: Protein fragments that build up in the spaces between nerve cells, disrupting communication and triggering immune responses.

Amyloid PET Scan: A specialized nuclear imaging test that uses radioactive tracers to visualize and measure the density of amyloid-beta plaques in the living brain.

Atrophy: The wasting away or shrinking of brain tissue, often measured via MRI to support a clinical diagnosis of dementia or Alzheimer’s.

B

Biomarkers: Measurable biological indicators, such as proteins found in blood or cerebrospinal fluid, used to identify the underlying pathology of a disease.

Blood Biomarkers: Emerging, less-invasive diagnostic tests that measure specific proteins like p-tau or neurofilament levels in blood plasma to detect Alzheimer’s pathology.

C

CSF Analysis (Cerebrospinal Fluid): A diagnostic procedure involving a lumbar puncture to measure levels of tau and amyloid-beta proteins in the fluid surrounding the brain and spinal cord.

CT Scan (Computed Tomography): A diagnostic imaging test using X-rays to create detailed cross-sectional images of the brain; used primarily to rule out other causes of cognitive decline such as tumors or strokes.

Clock Drawing Test (CDT): A brief cognitive screening task where a patient is asked to ask to draw a clock face; it evaluates visuospatial and executive function.

Cognitive Screening: The process of using standardized tests to objectively measure an individual’s mental functions, such as memory, orientation, and attention.

Community-based Care: Healthcare and support services provided within the local community, such as daycare centers, home-based nursing, and local support groups, rather than in institutional settings.

Cube Copying Test: A visuospatial assessment task used during neuropsychological evaluations to test a patient’s ability to replicate geometric shapes.

D

Dementia: An umbrella term for a range of neurological conditions characterized by a decline in memory, language, and thinking skills severe enough to interfere with daily life.

Dementia-friendly Society: A community or national environment where citizens and businesses are trained to understand, respect, and support the needs of people living with dementia.

Disease-modifying Therapies (DMTs): A new class of treatments, such as monoclonal antibodies (e.g., Lecanemab), designed to target the underlying biological causes of Alzheimer’s rather than just managing symptoms.

E

Early-Onset Alzheimer’s: A form of the disease that affects people younger than age 65, often linked to the familial genes.

Executive Function: Higher-level mental skills including planning, focusing, and multitasking; these are often what the Clock Drawing Test evaluates.

F

FDG-PET: A type of PET scan that measures glucose metabolism in the brain to identify patterns characteristic of different dementia subtypes.

Familial Alzheimer’s Disease: A rare, genetic form of the disease linked to mutations in specific genes (APP, PSEN1, PSEN2) that typically presents with early-onset symptoms.

Frontotemporal Dementia (FTD): A type of dementia caused by progressive nerve cell loss in the frontal or temporal lobes, leading to significant changes in behavior, personality, and language.

G

General Practitioner (GP): A primary care physician who acts as the first point of contact and gatekeeper for dementia diagnosis, providing initial assessments and referrals to specialists.

Genotyping: The analysis of an individual’s DNA to identify specific genetic variations associated with dementia risk or causation.

H

Hidden Cost: The indirect economic impacts of dementia, such as the loss of income for family members who must reduce working hours or leave their jobs to provide care.

I

Informal Care / Informal Caregiver: Unpaid care provided by family members, spouses, or friends, which represents the vast majority of long-term support for people living with dementia.

J

Japanese Cognitive Function Test (J-Cog): A specialized cognitive assessment tool used to evaluate mental and functional status in specific research or regional contexts.

L

Lewy Body Dementia (LBD): A type of progressive dementia that leads to a decline in thinking, reasoning, and independent function due to abnormal microscopic deposits that damage brain cells.

Long-Term Care Insurance (LTCI): A specialized branch of insurance, found in systems like Germany and Singapore, that provides financial subsidies for daily living assistance and nursing care.

M

Memory Clinic: A specialized, often multidisciplinary center focused on the expert diagnosis, management, and treatment of dementia and cognitive disorders.

Mild Cognitive Impairment (MCI): An intermediate stage between normal aging and dementia where memory or thinking problems are noticeable but don’t yet prevent daily functioning.

Mini-Mental State Examination (MMSE): A 30-point standardized questionnaire used to measure cognitive impairment by testing orientation, recall, and attention.

Montreal Cognitive Assessment (MoCA): A cognitive screening tool designed to be more sensitive than the MMSE, particularly for identifying Mild Cognitive Impairment.

MRI Scan (Magnetic Resonance Imaging): A non-invasive technology using magnetic fields to produce detailed images of brain structure; used to assess brain atrophy and rule out secondary causes.

N

National Dementia Plan: A formal government strategy outlining a coordinated response to manage dementia diagnosis, care, research, and awareness at a national level.

National Health Insurance (NHI): A government-funded or regulated healthcare system providing universal or subsidized medical services to citizens.

Neuroimaging: The use of advanced techniques, such as CT, MRI, and PET, to visualize the structure and function of the brain for diagnostic purposes.

Neuroinflammation: The brain’s immune response to damage or protein buildup; while initially protective, chronic inflammation can accelerate neurodegeneration.

O

Out-of-Pocket Costs: Direct payments made by patients or their families for medical services, tests, or care that are not covered by insurance or public subsidies.

P

Preclinical Alzheimer’s: The stage where brain changes (like amyloid buildup) are present but no outward symptoms are yet visible.

S

Synaptic Loss: The destruction of synapses (the gaps where neurons communicate), which is often the strongest correlate to cognitive decline.

T

Tau Tangles: Twisted fibers of a protein called tau that build up inside nerve cells, destroying the cell’s transport system.

V

Vascular Dementia: The second most common type of dementia, caused by conditions that block or reduce blood flow to the brain, like strokes.