Bolivia

Research conducted in November 2025

Bolivia provides universal health coverage through the Unified Health System (SUS) and allocates approximately 8.43% of its GDP to health. Diagnosis typically begins in primary care using screening tools such as the Mini-Mental State Examination (MMSE), with referral through SUS to neurology or geriatrics for further assessment, including neuroimaging. Treatment primarily involves donepezil and memantine, which are largely covered under SUS. Key care facilities include Hospital Viedma and Hospital Arco Iris, with imaging services available at national centres in Miraflores. Civil society engagement is led by Asociación Alzheimer Bolivia (AAB), while Law 4034 mandates the establishment of SEDEGES-run support centres, although implementation remains uneven across regions. Research activity is supported by institutions such as UMSA and Hospital de Clínicas, UMSS in Cochabamba, and sites in Santa Cruz, alongside participation in regional initiatives like LatAm-FINGERS and cohort studies. While there have been some steps toward developing a national dementia plan, progress has largely stalled.

Overall
AD Rating
Diagnostic Pathway
Bolivia maintains a formal referral pathway from primary care to specialists using structural imaging, though the system is hindered by structural bottlenecks and prolonged wait times.
Specialized Care
Standard symptomatic medications are largely subsidized and covered by the state health system, but specialized care is primarily concentrated in major urban centers.
Caregiver Support
While a legal framework for support centers exists, implementation is uneven across regions, leaving NGOs to provide the primary backbone of education and peer support.
National Policies
Bolivia lacks a dedicated national dementia strategy, with current efforts fragmented into specific laws rather than a cohesive, budgeted national plan.
Access to ATT-s
No therapies approved.
Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Highlights

Health system
Universal, Government Funded, Public Provisions
ADI member association(s)
Asociación Alzheimer Bolivia (AAB)
National dementia plan
/
Dementia plan funding
No plan
Dementia prevalence rate
298.52
Dementia incidence rate
52.91
*per 100k Population
Prevalence Rate (per 100,000): 
This measures the total number of existing cases (both old and new) in a population at a specific point in time, divided by the total population and multiplied by 100,000. It tells you the overall "burden" or how widespread a condition is at that moment.
Incidence Rate (per 100,000): 
This measures the number of new cases that develop in a population over a specific period (usually one year), divided by the population at risk and multiplied by 100,000. This tells you the "speed" or risk of contracting the condition.

Population

12,581,843

Median age

25.2

Health expenditure (% of GDP)

8.71

Diagnosis

In Bolivia, dementia diagnosis begins in primary care with assessment of memory loss and functional decline using DSM/ICD-aligned screening, typically MMSE/MEC. Suspected cases are referred through the SUS via a Boleta de Referencia to neurology, geriatrics, or psychiatry for comprehensive evaluation, including MoCA or ACE-III, labs, and CT or MRI. PET imaging, genetic testing, and biomarkers are not standard. Waiting times often exceed norms, especially in neurology. MRI may be SUS-covered, while public CT tariffs list 300 BOB and private services are higher.

Diagnosis pathway

Dementia pathways begin in primary care, where clinicians assess memory loss and functional decline through medical history, progressive cognitive symptom review, and basic cognitive screening aligned with DSM/ICD criteria. Suspected or complex cases are referred via the SUS system using a Boleta de Referencia to neurology, geriatrics, or psychiatry for comprehensive specialist evaluation and differential diagnosis, including Alzheimer’s disease.

Individuals or family members typically present to a primary care clinic with concerns about memory loss or functional decline. Primary care staff conduct an initial clinical assessment: medical history, review of progressive cognitive symptoms, and basic cognitive screening guided by national protocols that reference Diagnostic and Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases (ICD) criteria for dementia and distinguish Alzheimer’s disease from other causes.

When dementia is suspected or cases are complex, primary care must issue a Boleta de Referencia with clinical information to refer the person to a second- or third-level facility (neurology, geriatrics, or psychiatry) for specialist evaluation, per the Unified Health System (SUS) referral guide. The referral should be justified, timely, and include prior test results to facilitate specialist access.

Specialists conduct a diagnostic work-up to differentiate Alzheimer’s disease from other types of dementia. National neurology guidelines for diagnosis and treatment include “demencia tipo Alzheimer” alongside other primary and secondary dementias, providing a framework for differential diagnosis and clinical management within Bolivia’s health system.

Wait times

Long wait ime (expected)

Evidence indicates waiting times in Bolivia’s public system often exceed internal norms, particularly in high-demand specialties like neurology, pointing to structural delays in dementia care.

General studies on public-service waiting times in Bolivia highlight that waits often exceed internal norms, with people commonly waiting beyond intended thresholds for attention in public facilities, pointing to structural bottlenecks in staffing and scheduling, especially for high-demand specialties like neurology. While not dementia-specific, this supports the expectation of prolonged waits at key steps in the pathway.

Diagnosis cost

Mostly or fully covered

Under the SUS, advanced imaging such as MRI can be fully covered for eligible patients, with no direct payment required. Public tariff tables list CT at 300 BOB, while private providers report higher prices for MRI, consultations, and diagnostic imaging services.

The Ministry of Health indicates that advanced imaging (e.g., MRI) can be covered under the SUS for eligible patients, meaning no out-of-pocket cost for the study itself when authorized through the public pathway. A ministerial resolution table lists procedure tariffs; for example, “Tomografía Axial Computarizada (cualquier segmento)” shows a reference amount of 300 Bolivian peso (BOP) in the tariff list, illustrating public pricing benchmarks used administratively. People also have the option to use the private sector which is not covered by insurance.

Cognitive tests

Available

Primary care often starts with Mini-Mental State Examination (MMSE) due to familiarity and time constraints. If impairment is suspected, referral via SUS to specialist services is made, where Montreal Cognitive Assessment (MoCA) and Addenbrooke’s Cognitive Examination III (ACE-III) and targeted neuropsychological tests may be used as resources permit, alongside laboratory and imaging exams, per national norms.

Imaging tests

Commonly used

Bolivia’s public pathway uses structural neuroimaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), where available, ordered by specialists as part of the Alzheimer’s disease evaluation per national norms, accessed through the SUS referral system. While advanced positron emission tomography (PET) biomarkers are not described as routine in these national documents.

Genetic tests

There is no clear public documentation that Apolipoprotein E (APOE) risk typing or clinically validated predictive Alzheimer’s disease gene panels are offered routinely in the public health system.

Biomarker tests

Rarely used

There is no public evidence of routine, widely available in-country cerebrospinal fluid (CSF) or plasma biomarker testing in official health-system documents or laboratory service listings. Access to these specialised biomarker assays in practice is therefore likely limited to research centres. One study argues that recently updated Alzheimer’s disease diagnostic criteria, which rely heavily on biomarker evidence such as PET imaging and CSF analysis, are difficult to implement across much of Latin America and the Caribbean due to limited access to advanced technology, trained specialists, and region-specific normative data.

Cognitive Tests

Available

Primary care often starts with Mini-Mental State Examination (MMSE) due to familiarity and time constraints. If impairment is suspected, referral via SUS to specialist services is made, where Montreal Cognitive Assessment (MoCA) and Addenbrooke’s Cognitive Examination III (ACE-III) and targeted neuropsychological tests may be used as resources permit, alongside laboratory and imaging exams, per national norms.

Imaging Tests

Commonly used

Bolivia’s public pathway uses structural neuroimaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), where available, ordered by specialists as part of the Alzheimer’s disease evaluation per national norms, accessed through the SUS referral system. While advanced positron emission tomography (PET) biomarkers are not described as routine in these national documents.

Genetic Tests

There is no clear public documentation that Apolipoprotein E (APOE) risk typing or clinically validated predictive Alzheimer’s disease gene panels are offered routinely in the public health system.

Biomarker Tests

Rarely used

There is no public evidence of routine, widely available in-country cerebrospinal fluid (CSF) or plasma biomarker testing in official health-system documents or laboratory service listings. Access to these specialised biomarker assays in practice is therefore likely limited to research centres. One study argues that recently updated Alzheimer’s disease diagnostic criteria, which rely heavily on biomarker evidence such as PET imaging and CSF analysis, are difficult to implement across much of Latin America and the Caribbean due to limited access to advanced technology, trained specialists, and region-specific normative data.

Treatment & Care

Bolivia lacks dedicated memory clinics, but dementia care is provided through major hospitals like Hospital Arco Iris, Hospital Viedma, and the Complejo Hospitalario de Miraflores, with support from AAB. SUS-eligible patients generally receive covered follow-up care and medicines, while private consultations cost around $29. Public SEDEGES centers and AAB provide caregiver education, peer support, and connections to local specialists nationwide, established under Law 4034.

Specialized facilities and services

Although Bolivia lacks dedicated network of memory clinics, dementia services are concentrated in major public hospitals. Hospital Arco Iris and Hospital Viedma act as specialist neurology hubs, and the Complejo Hospitalario de Miraflores supports advanced diagnostics. The Asociación Alzheimer Bolivia connects families to trained clinicians, caregiver education, and local support networks across multiple departments.

Hospital Arco Iris is a publicly accredited second-level hospital with neurology and diagnostic imaging capacity; used by SUS. While not specialised only in Alzheimer’s disease, it functions as a specialist access point.

National referral complex Miraflores is a multi-institutes with national coverage with new CT and angiography equipment deployments. This indicates advanced diagnostics are available at certain national centers in La Paz. People living with dementia referred by SUS can be imaged in such complexes as part of workups.

Hospital Viedma is a large public hospital frequently cited in local reporting with heavy demand for neurology dates. While not a dedicated memory clinic, this is a primary public entry point for specialist neurology, indicating where Alzheimer’s disease evaluations can be found.

Asociación Alzheimer Bolivia (AAB) and its departmental chapters provide carer education, awareness, and connections to local specialists and services across several departments (e.g., Santa Cruz, La Paz, Cochabamba). These chapters are valuable gateways to locate clinicians familiar with Alzheimer’s disease and support resources.

No specific network of memory clinics was found via online search.

Approved medication

Generic Name Trade Name Used for
Donepezil Aricept, Aricept ODT, Adlarity, Eranz, Memac, Alzepil, Davia, Donecept, Donep, Donepex, Donesyn, Dopezil, Yasnal, Memorit, Pezale, Redumas, Zolpezil, Namzaric* Donepezil is indicated for the symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Memantine Namenda, Namenda XR, Ebixa, Memary, Axura, Akatinol, Maruxa, Nemdatine, Namzaric* Treatment of adult patients with moderate to severe Alzheimer’s disease.

*Namzaric = combination of Donepezil and Memantine

Treatment cost

For SUS-eligible patients, treatment and follow-up care provided through public hospitals are generally covered with no out-of-pocket cost when properly referred and authorized. This includes specialist follow-ups and medicines on the national essential list when stocked.

Caregiver support

Bolivia’s Law 4034 created public support centers for Alzheimer’s and dementia under SEDEGES, providing staff and administrative support for families and caregivers, though implementation varies by region. Complementing this, AAB offers caregiver education, awareness activities, peer support, and connections to local specialists and SEDEGES centers nationwide.

Legal framework for support centres (SEDEGES): Bolivia enacted Law 4034 creating centres to support people living with Alzheimer’s disease and other dementias, administered by departmental social services (SEDEGES). The law mandates provision of staff and administration via prefectures/SEDEGES, establishing a public support infrastructure for families and carers.

Caregiver education and community support: The Asociación Alzheimer Bolivia (AAB) operates chapters (e.g., Santa Cruz, national network) that offer carer education, awareness activities, and peer support, and help connect families to local specialists and SEDEGES centres.

Policy

Bolivia has dementia support centres under Ley 4034 but lacks a national dementia plan. Advocacy by ADI and Asociación Alzheimer Bolivia aims to develop a comprehensive strategy, addressing regional policy gaps.

National dementia plan

In Bolivia there is no current national strategy. Bolivia has a specific law (Ley 4034, 2009) that mandates creating support centres and developing programs for people living with Alzheimer’s disease and other dementias, but this is not a “Plan Nacional de Demencia” or national strategy framework.

Upcoming plans

Alzheimer’s Disease International (ADI) has recently highlighted Bolivia as a country where advocacy is ongoing and urged policymakers to develop a National Dementia Plan. ADI has engaged directly with Asociación Alzheimer Bolivia to build momentum, indicating that no plan is yet in place.

Policy gaps

Legal barriers

The institutional framework in Bolivia reinforces Alzheimer’s disease stigma through judicial interdiction, governed by the Civil Code and the Code of Families. This legal mechanism allows a court to declare an individual “absolutely incapable” due to cognitive impairment, effectively stripping them of their legal personality. Once interdicted, people can no longer sign contracts, manage assets, or make their own healthcare decisions.

Cultural barriers

In rural Andean and Amazonian regions, sudden behavioral changes in older adults – such as agitation, paranoia, or night wandering – may be interpreted as “possession” or the result of brujería (witchcraft). This can lead to the exclusion of the person, as neighbors and even some family members may fear being “contaminated” by the person.

Shifting demographic patterns and urban migration are eroding traditional community support for older adults, leaving many of them with diminished family care networks.

Research

Regional initiatives such as “No te olvides de mí” help Bolivia raise dementia awareness and promote early contact with primary care, which reinforces clinical pathways and encouraging timely help-seeking.

Clinical trials and registries

The regulatory authority responsible for overseeing and approving all clinical trials in Bolivia is the Agencia Estatal de Medicamentos y Tecnologías en Salud (AGEMED).

Selected innovative methods

Bolivia is strengthening dementia awareness and prevention through regional initiatives like “No te olvides de mí” and its participation in the LatAm-FINGERS clinical trial on lifestyle interventions. These efforts are bolstered by research on the indigenous Tsimane population, whose active subsistence lifestyles contribute to remarkably low dementia rates and slower age-related brain loss.

Bolivia has participated in regional initiatives to improve mental health and dementia awareness and pathways (e.g., “No te olvides de mí” in Andean countries), which have aimed to strengthen community recognition and help-seeking; these complement clinical pathways by encouraging earlier contact with primary care.

Research on the Tsimane, an indigenous forager-horticulturalist population in the Bolivian Amazon, shows that they experience unusually healthy aging outcomes compared with industrialised populations. They have an exceptionally low prevalence of dementia – far lower than in high-income countries – and exhibit significantly slower age-related brain volume loss likely linked to their physically active subsistence lifestyle and low cardiovascular risk factors despite high infection rates.

Bolivia is a participating country in the major multi-national clinical trial LatAm-FINGERS. The study evaluates how multidomain lifestyle interventions (including diet, physical exercise, and cognitive training) can prevent or delay cognitive decline in older adults.

Support

Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

There are no targeted dementia initiatives or media outlets in Bolivia, with AAB serving as the primary source of updates, events, and awareness content.

Selected national associations, patient family associations, NGOs:

Asociación Alzheimer Bolivia (AAB)

Selected initiatives

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Dedicated media outlets

Asociación Alzheimer Bolivia (AAB) publishes updates, event notices, and awareness content across chapters; these function as the most consistent, dementia-specific communication streams in Bolivia.

Understanding the terms

This section explains key terms used throughout the text to help readers better understand the exploration concepts.
Open Term Glossary
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Contents

Understanding the Terms

Terms used throughout this website are explained below.
A

Amyloid-Targeting Therapies (ATT): A class of disease-modifying treatments, primarily monoclonal antibodies, designed to identify and remove amyloid-beta plaques from the brain to slow cognitive and functional decline in early-stage Alzheimer’s. Examples include Lecanemab and Donanemab.

Aphasia: A language disorder that affects a person’s ability to communicate, often seen early in Frontotemporal Dementia.

APOE ε4 Allele: A genetic variant of the Apolipoprotein E gene that is a major risk factor for late-onset Alzheimer’s disease; while not a causative gene, its presence increases the likelihood of developing the condition.

Acetylcholinesterase Inhibitors: A class of medications, including Donepezil, Rivastigmine, and Galantamine, used to treat cognitive symptoms by increasing levels of chemical messengers in the brain.

Advance Directives (DAT): Legal documents, such as Disposizioni Anticipate di Trattamento in Italy, that allow individuals to specify their future medical treatment and care preferences while they still have the capacity to do so.

Alzheimer’s Disease (AD): The most common cause of dementia, characterized by a progressive neurodegenerative decline caused by the accumulation of amyloid plaques and tau tangles in the brain.

Amyloid-beta Plaques: Protein fragments that build up in the spaces between nerve cells, disrupting communication and triggering immune responses.

Amyloid PET Scan: A specialized nuclear imaging test that uses radioactive tracers to visualize and measure the density of amyloid-beta plaques in the living brain.

Atrophy: The wasting away or shrinking of brain tissue, often measured via MRI to support a clinical diagnosis of dementia or Alzheimer’s.

B

Biomarkers: Measurable biological indicators, such as proteins found in blood or cerebrospinal fluid, used to identify the underlying pathology of a disease.

Blood Biomarkers: Emerging, less-invasive diagnostic tests that measure specific proteins like p-tau or neurofilament levels in blood plasma to detect Alzheimer’s pathology.

C

CSF Analysis (Cerebrospinal Fluid): A diagnostic procedure involving a lumbar puncture to measure levels of tau and amyloid-beta proteins in the fluid surrounding the brain and spinal cord.

CT Scan (Computed Tomography): A diagnostic imaging test using X-rays to create detailed cross-sectional images of the brain; used primarily to rule out other causes of cognitive decline such as tumors or strokes.

Clock Drawing Test (CDT): A brief cognitive screening task where a patient is asked to ask to draw a clock face; it evaluates visuospatial and executive function.

Cognitive Screening: The process of using standardized tests to objectively measure an individual’s mental functions, such as memory, orientation, and attention.

Community-based Care: Healthcare and support services provided within the local community, such as daycare centers, home-based nursing, and local support groups, rather than in institutional settings.

Cube Copying Test: A visuospatial assessment task used during neuropsychological evaluations to test a patient’s ability to replicate geometric shapes.

D

Dementia: An umbrella term for a range of neurological conditions characterized by a decline in memory, language, and thinking skills severe enough to interfere with daily life.

Dementia-friendly Society: A community or national environment where citizens and businesses are trained to understand, respect, and support the needs of people living with dementia.

Disease-modifying Therapies (DMTs): A new class of treatments, such as monoclonal antibodies (e.g., Lecanemab), designed to target the underlying biological causes of Alzheimer’s rather than just managing symptoms.

E

Early-Onset Alzheimer’s: A form of the disease that affects people younger than age 65, often linked to the familial genes.

Executive Function: Higher-level mental skills including planning, focusing, and multitasking; these are often what the Clock Drawing Test evaluates.

F

FDG-PET: A type of PET scan that measures glucose metabolism in the brain to identify patterns characteristic of different dementia subtypes.

Familial Alzheimer’s Disease: A rare, genetic form of the disease linked to mutations in specific genes (APP, PSEN1, PSEN2) that typically presents with early-onset symptoms.

Frontotemporal Dementia (FTD): A type of dementia caused by progressive nerve cell loss in the frontal or temporal lobes, leading to significant changes in behavior, personality, and language.

G

General Practitioner (GP): A primary care physician who acts as the first point of contact and gatekeeper for dementia diagnosis, providing initial assessments and referrals to specialists.

Genotyping: The analysis of an individual’s DNA to identify specific genetic variations associated with dementia risk or causation.

H

Hidden Cost: The indirect economic impacts of dementia, such as the loss of income for family members who must reduce working hours or leave their jobs to provide care.

I

Informal Care / Informal Caregiver: Unpaid care provided by family members, spouses, or friends, which represents the vast majority of long-term support for people living with dementia.

J

Japanese Cognitive Function Test (J-Cog): A specialized cognitive assessment tool used to evaluate mental and functional status in specific research or regional contexts.

L

Lewy Body Dementia (LBD): A type of progressive dementia that leads to a decline in thinking, reasoning, and independent function due to abnormal microscopic deposits that damage brain cells.

Long-Term Care Insurance (LTCI): A specialized branch of insurance, found in systems like Germany and Singapore, that provides financial subsidies for daily living assistance and nursing care.

M

Memory Clinic: A specialized, often multidisciplinary center focused on the expert diagnosis, management, and treatment of dementia and cognitive disorders.

Mild Cognitive Impairment (MCI): An intermediate stage between normal aging and dementia where memory or thinking problems are noticeable but don’t yet prevent daily functioning.

Mini-Mental State Examination (MMSE): A 30-point standardized questionnaire used to measure cognitive impairment by testing orientation, recall, and attention.

Montreal Cognitive Assessment (MoCA): A cognitive screening tool designed to be more sensitive than the MMSE, particularly for identifying Mild Cognitive Impairment.

MRI Scan (Magnetic Resonance Imaging): A non-invasive technology using magnetic fields to produce detailed images of brain structure; used to assess brain atrophy and rule out secondary causes.

N

National Dementia Plan: A formal government strategy outlining a coordinated response to manage dementia diagnosis, care, research, and awareness at a national level.

National Health Insurance (NHI): A government-funded or regulated healthcare system providing universal or subsidized medical services to citizens.

Neuroimaging: The use of advanced techniques, such as CT, MRI, and PET, to visualize the structure and function of the brain for diagnostic purposes.

Neuroinflammation: The brain’s immune response to damage or protein buildup; while initially protective, chronic inflammation can accelerate neurodegeneration.

O

Out-of-Pocket Costs: Direct payments made by patients or their families for medical services, tests, or care that are not covered by insurance or public subsidies.

P

Preclinical Alzheimer’s: The stage where brain changes (like amyloid buildup) are present but no outward symptoms are yet visible.

S

Synaptic Loss: The destruction of synapses (the gaps where neurons communicate), which is often the strongest correlate to cognitive decline.

T

Tau Tangles: Twisted fibers of a protein called tau that build up inside nerve cells, destroying the cell’s transport system.

V

Vascular Dementia: The second most common type of dementia, caused by conditions that block or reduce blood flow to the brain, like strokes.