Honduras

Honduras’ dementia response is constrained by limited system capacity, incomplete universal health coverage, and high financial exposure. Care is delivered through general primary and specialist services rather than a dedicated dementia pathway, while out-of-pocket spending remains extremely high (51.71% of total health expenditure in 2021), reflecting gaps in effective coverage and pushing families toward private care to overcome public-sector delays. These dynamics amplify inequities, delay diagnosis, and fragment continuity of care, particularly for rural and low-income households. Within this context, the Asociación Hondureña de Alzheimer provides essential awareness, carer education, and navigation support, helping to mitigate, though not replace, system shortfalls. Despite ongoing UHC-oriented reforms, the absence of a formal, standardized national dementia plan remains the key missing system organiser, limiting coordination, financial protection, and scalable service delivery.

Overall
AD Rating
Diagnostic Pathway
The diagnostic pathway is unprotocolised, relying on clinical presentation and symptom-driven case-finding in primary care before referral to urban specialists.
Specialized Care
Access to dementia care is highly restricted, and specialised anti-dementia agents are not guaranteed under the National List of Essential Medicines, forcing a heavy reliance on expensive private pharmacies.
Caregiver Support
The state provides no dedicated caregiver allowances or formal long-term care services, leaving the burden of daily assistance entirely on family members and local NGOs.
National Policies
Honduras does not have an active or adopted national dementia strategy, folding cognitive health discussions loosely into general health and aging laws.
Access to ATT-s
No therapies approved.
Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Highlights

Health system
Non-universal, Mixed funding (Mixed provision)
National dementia plan
Dementia plan funding
No plan
Dementia prevalence rate
315
Dementia incidence rate
56
*per 100k Population
Prevalence Rate (per 100,000): 
This measures the total number of existing cases (both old and new) in a population at a specific point in time, divided by the total population and multiplied by 100,000. It tells you the overall "burden" or how widespread a condition is at that moment.
Incidence Rate (per 100,000): 
This measures the number of new cases that develop in a population over a specific period (usually one year), divided by the population at risk and multiplied by 100,000. This tells you the "speed" or risk of contracting the condition.

Population

11,110,104

Median age

24.6

Health expenditure (% of GDP)

8.3

Diagnosis

Suspected dementia entry flows through public primary care or private general practitioners. Complex cases are referred to neurologists, psychiatrists, or geriatricians, but system-wide constraints and long public queues prompt frequent private self-referrals. Wait times are unmeasured nationally, with rural areas facing severe resource and doctor shortages. Standard cognitive tools include Spanish versions of the MMSE and MoCA. Structural neuroimaging like CT and MRI is restricted to urban tertiary centres, while PET scans, genetic screenings, and fluid biomarkers remain unavailable publicly. High out-of-pocket spending forms a central gatekeeper to receiving a complete work-up.

Diagnosis pathway

Most individuals enter care through public primary care or private general practitioners. Complex cases are referred to specialists, but shortages and long public sector queues push families toward private pathways. Families frequently navigate the system informally or delay specialist consultations until behavioural symptoms disrupt functioning. The Asociación Hondureña de Alzheimer (ASHALZ) provides vital non-clinical education, caregiver support, and signposting to help households navigate this highly fragmented ecosystem.

In Honduras, most people with suspected dementia enter care through public primary care facilities or private general practitioners/internists, particularly in urban areas. When cognitive decline becomes more evident or complex, people are referred, where feasible, to specialist assessment (neurology, psychiatry, or geriatrics) for diagnostic confirmation and differential diagnosis. In practice, system wide capacity constraints, including limited specialists, diagnostic infrastructure, and long public-sector queues, mean that families frequently rely on private sector routes to obtain specialist opinions or faster assessments. Informal navigation is common, with some families alternating between public and private services or delaying specialist contact until symptoms become functionally or behaviorally disruptive. Dementia guidance and awareness are supported by the national Alzheimer’s Disease International (ADI) member, Asociación Hondureña de Alzheimer (ASHALZ), which acts as a key civil society node for education, carer support, and signposting. While not a clinical provider, the association helps families understand symptoms, seek evaluation, and access carer resources in a fragmented system.

Wait times

Long wait time (expected)

Honduras does not publish standardised, dementia-specific wait time indicators. Delays stem from low specialist availability, urban concentration, and out-of-pocket reliance. Rural shortages are severe, with roughly 0.5 physicians per 1,000 people as of 2020 and ongoing emigration further weakening infrastructure. Geographic and financial barriers lead to widespread unmet needs and prolonged timelines for lower-income and rural groups rather than a uniform waiting list.

Honduras does not publish standardised, dementia-specific national wait time indicators in major public sources. Instead, delays are driven by structural and financial constraints: limited specialist availability in the public sector, geographic concentration of services in larger cities, and heavy reliance on out-of-pocket payment. Access problems are most acute in rural areas, where facilities are distant, under-resourced, and staffed by a very limited workforce, approximately 0.5 physicians per 1,000 people as of 2020, with most concentrated in cities and ongoing emigration further weakening capacity. As a result, geographic and financial barriers combine to leave many health needs unmet, particularly outside urban centers. In practice, this results in uneven access and prolonged timelines, particularly for lower-income households and rural populations, rather than a single measurable national waiting list.

Diagnosis cost

Not covered

Diagnostic access is limited, with 18 percent of the population lacking healthcare and 83 percent in informal employment. Out-of-pocket costs constituted 51.7 percent of health expenditure in 2021, forcing households to fund consultations, tests, drugs, and neuroimaging. These cumulative expenses repeat over multiple visits, meaning ability to pay heavily governs diagnostic depth, leading to delayed or abandoned pathways among poorer households.

Honduras faces severe health system constraints: an estimated 18% of the population lacks access to any healthcare services, a vulnerability intensified by high informal employment (about 83%), which leaves many without stable coverage and at risk of sudden medical disenfranchisement. Financial exposure is a central constraint in dementia diagnosis in Honduras. According to the Pan American Health Organization, out-of-pocket spending accounted for approximately 51.7% of total health expenditure in 2021, placing Honduras among the highest out-of-pocket reliant health systems in the region. In practical terms, this means households frequently bear substantial costs for medical consultations, diagnostic work-up, medicines, and imaging, particularly when turning to the private sector to bypass delays or limited availability in public facilities. These costs are not one-off: dementia diagnosis often requires multiple visits, follow-up assessments, repeat imaging, and specialist consultations, compounding the financial burden over time. As a result, ability to pay strongly shapes not only the speed of diagnosis, but also its depth and quality, influencing whether patients receive timely specialist confirmation, comprehensive differential diagnosis, and appropriate follow-up. These dynamics reinforce inequities across income groups and between urban and rural populations, with poorer households more likely to experience delayed diagnosis, incomplete assessment, or abandonment of the diagnostic pathway altogether.

Cognitive tests

Available

There is no documented nationwide dementia screening program. Case finding is therefore symptom-driven, initiated through clinical presentation in primary care or during specialist consultation rather than through systematic early detection. Cognitive assessment is clinically determined and variable, forming part of routine work-up in specialist or hospital settings rather than a protocolized national pathway. While no standardised national test battery is mandated, widely used instruments such as the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) are available in Spanish, as across much of Central America, and are used in practice according to clinician preference and setting.

Imaging tests

Used in specific cases

Structural neuroimaging, computed tomography (CT) and magnetic resonance imagining (MRI), is typically part of the dementia differential diagnosis, particularly to exclude secondary or reversible causes. In Honduras, this capacity is concentrated in tertiary and larger regional hospitals, primarily in major urban centers, and access is strongly shaped by the payment route. In the public sector CT or MRI is available in referral hospitals but may involve delays, limited slots, or equipment constraints, while private imaging centers offer faster access at substantially higher cost. Positron emission tomography (PET) imaging (including FDG-PET or amyloid PET) is not part of routine clinical care and is not documented as available for dementia work-up within the public system; where obtained, it is typically accessed privately or off-island for selected cases, rather than as standard practice.

Genetic tests

There is no evidence that genetic testing for Alzheimer’s disease, such as apolipoprotein E (APOE) genotyping or familial dementia panels, is incorporated into routine public diagnostic pathways. Where genetic testing is pursued, it appears to be exceptional and case-specific, most often accessed through private providers or referral abroad, rather than embedded in standard clinical care.

Biomarker tests

Rarely used

Similarly, Alzheimer’s disease biomarkers, including cerebrospinal fluid (CSF) markers (Aβ, total tau, phosphorylated tau) and emerging blood-based biomarkers, are not part of routine diagnostic practice in Honduras. Any use is more plausibly limited to selected specialist or research contexts, or obtained through private care or evaluation abroad, rather than systematically available within the public health system.

Cognitive Tests

Available

There is no documented nationwide dementia screening program. Case finding is therefore symptom-driven, initiated through clinical presentation in primary care or during specialist consultation rather than through systematic early detection. Cognitive assessment is clinically determined and variable, forming part of routine work-up in specialist or hospital settings rather than a protocolized national pathway. While no standardised national test battery is mandated, widely used instruments such as the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) are available in Spanish, as across much of Central America, and are used in practice according to clinician preference and setting.

Imaging Tests

Used in specific cases

Structural neuroimaging, computed tomography (CT) and magnetic resonance imagining (MRI), is typically part of the dementia differential diagnosis, particularly to exclude secondary or reversible causes. In Honduras, this capacity is concentrated in tertiary and larger regional hospitals, primarily in major urban centers, and access is strongly shaped by the payment route. In the public sector CT or MRI is available in referral hospitals but may involve delays, limited slots, or equipment constraints, while private imaging centers offer faster access at substantially higher cost. Positron emission tomography (PET) imaging (including FDG-PET or amyloid PET) is not part of routine clinical care and is not documented as available for dementia work-up within the public system; where obtained, it is typically accessed privately or off-island for selected cases, rather than as standard practice.

Genetic Tests

There is no evidence that genetic testing for Alzheimer’s disease, such as apolipoprotein E (APOE) genotyping or familial dementia panels, is incorporated into routine public diagnostic pathways. Where genetic testing is pursued, it appears to be exceptional and case-specific, most often accessed through private providers or referral abroad, rather than embedded in standard clinical care.

Biomarker Tests

Rarely used

Similarly, Alzheimer’s disease biomarkers, including cerebrospinal fluid (CSF) markers (Aβ, total tau, phosphorylated tau) and emerging blood-based biomarkers, are not part of routine diagnostic practice in Honduras. Any use is more plausibly limited to selected specialist or research contexts, or obtained through private care or evaluation abroad, rather than systematically available within the public health system.

Treatment & Care

Honduras lacks a national network of memory clinics, leaving services fragmented and provider coordination limited to an ad hoc basis. Specialists are concentrated in Tegucigalpa and San Pedro Sula, without public multidisciplinary teams. Specialised anti-dementia drugs are omitted from the main essential medicines list, creating inconsistent public supplies and forcing a reliance on private pharmacies. High out-of-pocket expenses impede treatment adherence. Caregiving falls heavily on family members with scarce formal respite, though ASHALZ is developing the country’s first sliding-scale adult day care centre.

Specialized facilities and services

Honduras lacks a national network of memory clinics or dementia-specific specialist centres. Care services are fragmented, and ad hoc collaboration occurs without awareness of other relevant providers. Public specialist capacity and multidisciplinary teams are not systematically established and are concentrated in Tegucigalpa and San Pedro Sula. ASHALZ provides essential non-formal navigation and support to complement this limited infrastructure.

Honduras does not have a clearly documented national network of memory clinics or dementia-specific specialist centers. Dementia care is delivered through a range of health, social, and community organisations, but services remain fragmented and coordination between providers is limited. Organisations often have diverse connections and collaborate on an ad hoc basis, yet many are unaware of other relevant providers with whom they could coordinate, creating gaps in referrals, information sharing, and continuity of care. Specialist capacity is geographically concentrated in larger urban centers, particularly Tegucigalpa and San Pedro Sula, limiting access for rural populations. Multidisciplinary dementia teams, consisting of neurologists, geriatricians, psychologists and social workers, are not systematically established within the public sector, and care coordination often depends on family initiative and private referral. In this context, civil society actors, most notably the ASHALZ, play an important navigation and support role, complementing limited formal service infrastructure.

Approved medication

Generic Name Trade Name Used for
Donepezil Aricept, Aricept ODT, Adlarity, Eranz, Memac, Alzepil, Davia, Donecept, Donep, Donepex, Donesyn, Dopezil, Yasnal, Memorit, Pezale, Redumas, Zolpezil, Namzaric* Donepezil is indicated for the symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Rivastigmine Exelon, Exelon Patch, Prometax, Rivastach, Nimvastid Symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Symptomatic treatment of mild to moderately severe dementia in patients with idiopathic Parkinson’s disease.
Galantamine Razadyne, Razadyne ER, Reminyl, Reminyl XL, Nivalin, Lycoremine, Galsya Galantamine is indicated for the symptomatic treatment of mild to moderately severe dementia of the Alzheimer type.
Memantine Namenda, Namenda XR, Ebixa, Memary, Axura, Akatinol, Maruxa, Nemdatine, Namzaric* Treatment of adult patients with moderate to severe Alzheimer’s disease.

*Namzaric = combination of Donepezil and Memantine

Treatment cost

The elderly face severe cost barriers; 42 percent lack regular healthcare, 64 percent have no monthly income, and only 7 percent receive social pensions. Out-of-pocket spending accounts for roughly half of total health expenditure, placing follow-up, medications, and monitoring costs on families. These progressive costs influence whether care is maintained or discontinued, reinforcing geographic and socioeconomic inequities.

The older population is generally facing treatment cost challenges as 42% do not receive regular healthcare, 64% have no monthly income, and only 7% receive a social pension. Treatment costs represent a major barrier to sustained dementia care, with out-of-pocket spending accounting for roughly half of total health expenditure. Families, therefore, frequently bear the costs of follow-up consultations, medicines, diagnostic monitoring, and supportive therapies, especially when relying on private providers to obtain timely care. Over the course of a progressive condition such as dementia, these expenses accumulate, influencing whether treatment is initiated early, maintained consistently, or discontinued altogether. Financial exposure therefore affects not only access but also treatment adherence and quality of care, reinforcing socioeconomic and geographic inequities.

Caregiver support

Caregiver support is mostly non-governmental, as public long-term and respite services are scarce. PAHO promotes caregiver training tools like iSupport, but local uptake remains dependent on regional capacity. Families serve as the primary care providers. To address this gap, ASHALZ is supporting the creation of the country’s first sliding-scale Adult Day Care Centre to provide cognitive stimulation, therapies, and caregiver respite for an initial twenty families.

Carer support is predominantly non-governmental organisation (NGO)-linked rather than systematized within public services. The ASHALZ provides education, awareness raising, carer guidance, and signposting, serving as a key support pillar in a context where formal long-term care and respite services are limited. At the regional level, the Pan American Health Organization promotes carer skills training, most notably through World Health Organization (WHO) and Pan-American Health Organization (PAHO) iSupport resources, which can help bridge gaps in formal service provision, though uptake depends on local dissemination and capacity. Overall, carer challenges remain high, with families acting as the primary care providers for people living with dementia.

For example, The ASHALZ is supporting the creation of Honduras’ first Adult Day Care Center for people living with dementia, addressing a major gap in services for affected individuals and their families. The center will provide a safe environment, nutritious meals, social and cognitive stimulation, physical exercise, and individualized therapies, offering structured daytime care while enabling family caregivers to work and manage daily responsibilities. With services offered on a sliding scale fee structure to support low-income families, the initiative aims to improve quality of life and relieve carer challenges, with an initial impact expected for around 20 families, marking a significant step in dementia care infrastructure in Honduras.

Policy

Honduras lacks an operational national dementia strategy or any near-future plans, meaning dementia is addressed indirectly under generic health and ageing legislation. Major legal gaps exist because general laws fail to establish standardised pathways, explicit entitlements, long-term care protections, or distinct neurodegenerative policy categories. Culturally, symptoms are normalised as standard ageing, delaying early clinical presentation. Family-centric care expectations place a high load on female relatives, while persistent public stigma surrounding cognitive and behavioural deficits discourages open discussion and help-seeking.

National dementia plan

Initial meetings with government stakeholders have been held to discuss the development of a national dementia strategy; however these discussions have not yet resulted in further progress toward the adoption of a formal national plan. Dementia policy is therefore addressed indirectly, subsumed within general health legislation and ageing-related discussions rather than through a dedicated, time-bound strategy with defined responsibilities, funding, and monitoring indicators.

Upcoming plans

There have been no official announcements suggesting that a national dementia or Alzheimer’s disease plan will be adopted in Honduras in the near future.

Policy gaps

Legal barriers

Dementia care is governed by general health and social protection statutes rather than dementia-specific legal instruments. The General Health Law fails to define explicit entitlements, standardised diagnostic pathways, or minimum long-term care guidelines. Mental health regulations focus on severe mental illness, leaving neurodegenerative diseases legally under-specified. Fragmented social provisions do not codify caregiver rights, respite, or long-term packages, resulting in widespread access and financial protective variability.

Dementia care in Honduras is governed by general health and social protection laws rather than dementia-specific legal instruments, which creates structural gaps across the care continuum. Under the General Health Law, the organization of the national health system and access to public services are established, but the law does not define dementia-specific entitlements, standardised diagnostic pathways, referral triggers, or minimum long-term care standards for people living with cognitive disorders. Mental health–related regulations and programs primarily address severe mental illness and psychosocial conditions, and do not explicitly recognize neurodegenerative diseases such as Alzheimer’s disease and other dementias as a distinct policy category, leaving them legally under-specified. Social protection and elderly provisions exist in fragmented and non-specialized forms, but they do not codify dementia capable long-term care requirements, caregiver rights, respite, or structured support packages. Together, these legal gaps result in dementia being treated as a general clinical issue rather than a condition requiring coordinated, rights-based, and long-term statutory protection, reinforcing variability in access, quality, and financial protection.

Cultural barriers

Cognitive decline is widely normalised as a standard part of ageing, delaying clinical engagement until symptoms become highly severe. Strong family-centric care norms dictate that relatives, typically women, assume extensive caregiving roles with little formal backing, which reduces help-seeking. Stigma surrounding behavioural symptoms discourages open discussion, while limited literacy outside non-governmental organisations reinforces reliance on informal coping mechanisms.

Cultural perceptions further shape dementia care and interact with legal and system constraints. Cognitive decline is often normalized as a natural part of ageing, delaying recognition and clinical engagement until symptoms become severe. Strong family-centric care expectations mean that relatives, often women, assume caregiving responsibilities with limited formal support, reducing help-seeking and increasing caregiver load. Stigma surrounding mental and cognitive illness persists, particularly around behavioural symptoms, discouraging open discussion and early diagnosis. Limited dementia literacy outside NGO networks reinforces reliance on informal coping strategies rather than structured care pathways. These cultural factors, combined with weak legal recognition and high out-of-pocket costs, might contribute to late presentation, uneven access, and prolonged reliance on informal care for people living with dementia in Honduras.

Research

Academic research occurs at institutions like the National Autonomous University of Honduras. No active clinical drug trials or registries exist locally under the Ministry of Health, necessitating enrolment abroad. Innovation is oriented toward universal health coverage integration and primary care task-shifting rather than biomedical discoveries. The rollout of the interoperable Perinatal Information System Plus (SIP Plus) establishes a data governance foundation that could eventually support neurocognitive tracking. Risk analysis indicates that lower educational attainment, smoking, and depression are primary modifiable drivers of local prevalence.

Clinical trials and registries

There is no evidence that Honduras hosts clinical trials for Alzheimer’s disease drugs or disease-modifying therapies, and the country does not appear as a regular study site in major international trial registries. As a result, access to clinical trial participation generally requires referral or enrollment abroad, making such opportunities inaccessible for the vast majority of people living with dementia in Honduras. The Secretaría de Salud (SESAL) (Ministry of Health) and the Agencia de Regulación Sanitaria (ARSA) oversee the approval and ethical compliance of health research and medical treatments in the country.,

Selected innovative methods

Innovation is oriented toward service delivery and system integration rather than biomedical frameworks. Key levers focus on embedding dementia into primary health care strengthening and integrated service networks under universal health coverage reforms, utilising task-shifting and chronic-care platforms. Furthermore, the scalable implementation of the data-driven Perinatal Information System Plus (SIP Plus) demonstrates health information governance capacity that could later support neurocognitive patient tracking.

In the Honduran context, innovation in dementia care is service delivery and system integration oriented rather than biomedical. The most realistic lever for improvement lies in embedding dementia into primary health care strengthening and integrated service networks, in line with PAHO-supported reforms aimed at universal health coverage (UHC). This includes task-shifting to primary care, improving recognition and referral of cognitive impairment, integrating carer support into community services, and using existing chronic-care platforms to manage dementia as a long-term condition. Such approaches offer scalable gains without requiring high-cost specialist infrastructure.

In July 2024, Honduras advanced its health sector digital transformation through the implementation of the Perinatal Information System Plus (SIP Plus), led by the Ministry of Health (SESAL) with technical support from PAHO/WHO Honduras and the Latin American Center for Perinatology. Integrated within the country’s Electronic Health Record framework and grounded in Primary Health Care and Integrated Health Services Networks, SIP Plus enables standardized, real-time collection and analysis of health data, automated reporting of demographic and disease indicators, and improved decision-making. The integration of birth registration data, achieved in partnership with the National Registry of Persons and the National Institute of Statistics, marks a significant milestone in health information governance.

While SIP Plus is focused on maternal, neonatal, and reproductive health, its rollout is relevant to future dementia and Alzheimer’s disease care as evidence of Honduras’ capacity to deploy interoperable, data-driven health information systems at scale. This infrastructure provides a foundation that could be extended to support chronic and neurocognitive conditions, including standardised referral pathways, longitudinal patient tracking, and population-level surveillance, critical enablers for improving dementia care in a resource-constrained system.

A recent analysis of modifiable dementia risk factors in Latin America found that, in Honduras, the highest population attributable fractions (PAFs) for dementia were associated with lower educational attainment, smoking, and depression, suggesting that prevention efforts targeting these factors could have a substantial impact on reducing future dementia challenges.

Support

Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Dementia support is anchored by non-governmental groups like ASHALZ and the Carolina Honduras Health Foundation. ASHALZ coordinates public educational campaigns alongside PAHO to improve literacy and combat stigma. To stabilise pharmaceutical access, a UNOPS procurement partnership delivered over 40 million medicine units by June 2025. Grassroots initiatives include promoting the empathetic film A Kind of Madness and the Inter-American Restoration Corporation’s medical care microprojects for impoverished rural seniors. No standalone dementia-only media outlets exist, restricting public information to civil channels.

Selected national associations, patient family associations, NGOs:

La Asociación Hondureña de Alzheimer (ASHALZ) Hands 4 Life

Selected initiatives

ASHALZ organises national campaigns alongside PAHO/WHO to improve dementia literacy and reduce public stigma. To increase drug reliability across the Honduran Social Security Institute, a procurement partnership with UNOPS delivered over 40 million medicine units by June 2025. Additionally, ASHALZ highlighted the streaming film A Kind of Madness to build empathy, while the Inter-American Restoration Corporation provides free medical care microprojects for impoverished rural seniors.

World Alzheimer’s Day
As an ADI member, ASHALZ organizes national World Alzheimer’s Day and World Alzheimer’s Month campaigns, often in collaboration with PAHO/WHO Honduras, using public messaging, community outreach, and social media to reduce stigma and improve dementia literacy. Its activities typically include educational talks, caregiver guidance and training, information campaigns on early signs of dementia, and signposting to available services, alongside broader advocacy for improved policy attention and health-system preparedness. Through these campaigns, ASHALZ functions as a key connector between families, health professionals, and international partners in a system with limited formal dementia services.
The partnership between the United Nations Office for Project Services (UNOPS) and the Honduran Social Security Institute (IHSS) has substantially strengthened national medicine procurement and supply-chain capacity, with major scale-up between late 2024 and mid-2025. By June 2025, UNOPS had delivered over 40 million units of medicines under an expanded agreement, building on successive amendments that together exceed 100 million USD. Although not dementia-specific, this initiative is highly relevant to Alzheimer’s disease and dementia care in a system marked by high out-of-pocket spending and frequent stock constraints
improved procurement, logistics, and distribution across the IHSS network increase the reliability and affordability of essential medicines and treatments for comorbidities, reducing interruptions that disproportionately affect people living with dementia. As such, the programme serves as a critical enabling platform that could meaningfully support dementia care if cognitive-health priorities are explicitly integrated into formularies and distribution planning.
A Kind of Madness film
To raise awareness, The ALHAZ highlighted the film A Kind of Madness as a powerful tool for empathy and reflection on dementia. The movie tells the story of a 70-year-old man who takes his wife, who lives with dementia, on a final journey together, raising profound questions about memory, identity, love, and autonomy. Recommended for caregivers, families, professionals, and the wider public, the film is presented as a way to better understand the emotional and ethical challenges faced by people living with Alzheimer’s disease and those who care for them, and is available on major streaming platforms.
Healing and Hope for Honduras’ Forgotten Elderly project
The “Healing and Hope for Honduras’ Forgotten Elderly” microproject, led by the Inter-American Restoration Corporation, aims to improve access to healthcare for elderly people in rural Honduras who are living in poverty and often lack any medical support. The project focuses on providing free medical care to 100 elderly individuals, including regular check-ups, home visits, and treatment for chronic and acute conditions, addressing urgent health needs that would otherwise go unmet. By removing financial barriers to care, the initiative seeks to reduce preventable suffering, restore dignity, and improve quality of life for some of the most vulnerable seniors. Over the longer term, the organization aims to extend medical, dental, nutritional, and vitamin support to up to 4,000 underserved people, generating broader benefits for families and communities through improved health and wellbeing.

Dedicated media outlets

There is no documented dementia-only national media outlet in Honduras. Public communication on dementia appears to rely on NGO channels, social media, community outreach, and general public-health communications rather than a sustained, government-led media strategy. This reinforces the central role of civil society in shaping public understanding of dementia, while also highlighting the absence of systematic, state-led information dissemination.

Understanding the terms

This section explains key terms used throughout the text to help readers better understand the exploration concepts.
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Contents

Understanding the Terms

Terms used throughout this website are explained below.
A

Amyloid-Targeting Therapies (ATT): A class of disease-modifying treatments, primarily monoclonal antibodies, designed to identify and remove amyloid-beta plaques from the brain to slow cognitive and functional decline in early-stage Alzheimer’s. Examples include Lecanemab and Donanemab.

Aphasia: A language disorder that affects a person’s ability to communicate, often seen early in Frontotemporal Dementia.

APOE ε4 Allele: A genetic variant of the Apolipoprotein E gene that is a major risk factor for late-onset Alzheimer’s disease; while not a causative gene, its presence increases the likelihood of developing the condition.

Acetylcholinesterase Inhibitors: A class of medications, including Donepezil, Rivastigmine, and Galantamine, used to treat cognitive symptoms by increasing levels of chemical messengers in the brain.

Advance Directives (DAT): Legal documents, such as Disposizioni Anticipate di Trattamento in Italy, that allow individuals to specify their future medical treatment and care preferences while they still have the capacity to do so.

Alzheimer’s Disease (AD): The most common cause of dementia, characterized by a progressive neurodegenerative decline caused by the accumulation of amyloid plaques and tau tangles in the brain.

Amyloid-beta Plaques: Protein fragments that build up in the spaces between nerve cells, disrupting communication and triggering immune responses.

Amyloid PET Scan: A specialized nuclear imaging test that uses radioactive tracers to visualize and measure the density of amyloid-beta plaques in the living brain.

Atrophy: The wasting away or shrinking of brain tissue, often measured via MRI to support a clinical diagnosis of dementia or Alzheimer’s.

B

Biomarkers: Measurable biological indicators, such as proteins found in blood or cerebrospinal fluid, used to identify the underlying pathology of a disease.

Blood Biomarkers: Emerging, less-invasive diagnostic tests that measure specific proteins like p-tau or neurofilament levels in blood plasma to detect Alzheimer’s pathology.

C

CSF Analysis (Cerebrospinal Fluid): A diagnostic procedure involving a lumbar puncture to measure levels of tau and amyloid-beta proteins in the fluid surrounding the brain and spinal cord.

CT Scan (Computed Tomography): A diagnostic imaging test using X-rays to create detailed cross-sectional images of the brain; used primarily to rule out other causes of cognitive decline such as tumors or strokes.

Clock Drawing Test (CDT): A brief cognitive screening task where a patient is asked to ask to draw a clock face; it evaluates visuospatial and executive function.

Cognitive Screening: The process of using standardized tests to objectively measure an individual’s mental functions, such as memory, orientation, and attention.

Community-based Care: Healthcare and support services provided within the local community, such as daycare centers, home-based nursing, and local support groups, rather than in institutional settings.

Cube Copying Test: A visuospatial assessment task used during neuropsychological evaluations to test a patient’s ability to replicate geometric shapes.

D

Dementia: An umbrella term for a range of neurological conditions characterized by a decline in memory, language, and thinking skills severe enough to interfere with daily life.

Dementia-friendly Society: A community or national environment where citizens and businesses are trained to understand, respect, and support the needs of people living with dementia.

Disease-modifying Therapies (DMTs): A new class of treatments, such as monoclonal antibodies (e.g., Lecanemab), designed to target the underlying biological causes of Alzheimer’s rather than just managing symptoms.

E

Early-Onset Alzheimer’s: A form of the disease that affects people younger than age 65, often linked to the familial genes.

Executive Function: Higher-level mental skills including planning, focusing, and multitasking; these are often what the Clock Drawing Test evaluates.

F

FDG-PET: A type of PET scan that measures glucose metabolism in the brain to identify patterns characteristic of different dementia subtypes.

Familial Alzheimer’s Disease: A rare, genetic form of the disease linked to mutations in specific genes (APP, PSEN1, PSEN2) that typically presents with early-onset symptoms.

Frontotemporal Dementia (FTD): A type of dementia caused by progressive nerve cell loss in the frontal or temporal lobes, leading to significant changes in behavior, personality, and language.

G

General Practitioner (GP): A primary care physician who acts as the first point of contact and gatekeeper for dementia diagnosis, providing initial assessments and referrals to specialists.

Genotyping: The analysis of an individual’s DNA to identify specific genetic variations associated with dementia risk or causation.

H

Hidden Cost: The indirect economic impacts of dementia, such as the loss of income for family members who must reduce working hours or leave their jobs to provide care.

I

Informal Care / Informal Caregiver: Unpaid care provided by family members, spouses, or friends, which represents the vast majority of long-term support for people living with dementia.

J

Japanese Cognitive Function Test (J-Cog): A specialized cognitive assessment tool used to evaluate mental and functional status in specific research or regional contexts.

L

Lewy Body Dementia (LBD): A type of progressive dementia that leads to a decline in thinking, reasoning, and independent function due to abnormal microscopic deposits that damage brain cells.

Long-Term Care Insurance (LTCI): A specialized branch of insurance, found in systems like Germany and Singapore, that provides financial subsidies for daily living assistance and nursing care.

M

Memory Clinic: A specialized, often multidisciplinary center focused on the expert diagnosis, management, and treatment of dementia and cognitive disorders.

Mild Cognitive Impairment (MCI): An intermediate stage between normal aging and dementia where memory or thinking problems are noticeable but don’t yet prevent daily functioning.

Mini-Mental State Examination (MMSE): A 30-point standardized questionnaire used to measure cognitive impairment by testing orientation, recall, and attention.

Montreal Cognitive Assessment (MoCA): A cognitive screening tool designed to be more sensitive than the MMSE, particularly for identifying Mild Cognitive Impairment.

MRI Scan (Magnetic Resonance Imaging): A non-invasive technology using magnetic fields to produce detailed images of brain structure; used to assess brain atrophy and rule out secondary causes.

N

National Dementia Plan: A formal government strategy outlining a coordinated response to manage dementia diagnosis, care, research, and awareness at a national level.

National Health Insurance (NHI): A government-funded or regulated healthcare system providing universal or subsidized medical services to citizens.

Neuroimaging: The use of advanced techniques, such as CT, MRI, and PET, to visualize the structure and function of the brain for diagnostic purposes.

Neuroinflammation: The brain’s immune response to damage or protein buildup; while initially protective, chronic inflammation can accelerate neurodegeneration.

O

Out-of-Pocket Costs: Direct payments made by patients or their families for medical services, tests, or care that are not covered by insurance or public subsidies.

P

Preclinical Alzheimer’s: The stage where brain changes (like amyloid buildup) are present but no outward symptoms are yet visible.

S

Synaptic Loss: The destruction of synapses (the gaps where neurons communicate), which is often the strongest correlate to cognitive decline.

T

Tau Tangles: Twisted fibers of a protein called tau that build up inside nerve cells, destroying the cell’s transport system.

V

Vascular Dementia: The second most common type of dementia, caused by conditions that block or reduce blood flow to the brain, like strokes.