Poland

Poland stands out for its integration of academic research and clinical practice in Alzheimer’s care, with multiple universities and institutes actively conducting cutting-edge studies and hosting international clinical trials. A National Programme of Actions against Dementia 2025–2030 has been drafted and is undergoing ministerial consultation, though not yet adopted. Poland distinguishes itself through strong links between clinical practice and academic research, hosting major centres such as the University Hospital in Kraków, the Nencki Institute, and the IIMCB in Warsaw. Despite organisational gaps and regional disparities in diagnosis and access to imaging or biomarkers, the country benefits from an active network of NGOs, caregiver‑support programmes, and public awareness initiatives that increasingly frame dementia as a national health‑policy priority.

Overall
AD Rating
Diagnostic Pathway
Poland has a guideline-based and structured diagnostic pathway, but access constraints and limited use of advanced diagnostics create delays and bottlenecks.
Specialized Care
Poland offers a strong regional network for dementia care and reimbursed medications, with private options expanding access, though rural disparities and high private costs persist.
Caregiver Support
Poland offers solid financial support and legal recognition for caregivers, with some respite and community services, though gaps remain in consistency and specialised support.
National Policies
Poland is preparing its first national dementia strategy for 2025–2030, aiming to expand patient and caregiver support, improve systemic coordination, and enhance quality of life, but it has not yet been implemented or fully funded.
Access to ATT-s
ATT therapies approved; one reimbursed.
Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Highlights

Health system
Universal, Social Health insurance, Mixed provision
ADI member association(s)
Polish Alzheimer’s Association
National dementia plan
A draft has been discussed with ministry officials and parliamentary health committees but no adoption
Dementia plan funding
No plan
Dementia prevalence rate
1311
Dementia incidence rate
231
*per 100k Population
Prevalence Rate (per 100,000): 
This measures the total number of existing cases (both old and new) in a population at a specific point in time, divided by the total population and multiplied by 100,000. It tells you the overall "burden" or how widespread a condition is at that moment.
Incidence Rate (per 100,000): 
This measures the number of new cases that develop in a population over a specific period (usually one year), divided by the population at risk and multiplied by 100,000. This tells you the "speed" or risk of contracting the condition.

Population

38,140,910

Median age

42.5

Health expenditure (% of GDP)

7

Diagnosis

Dementia diagnosis in Poland typically begins in primary or specialist neurological care and follows European clinical guidelines. Assessment relies primarily on clinical evaluation and cognitive testing, most commonly the MMSE and MoCA, supported by structural imaging such as CT or MRI to exclude other causes. While core diagnostic services are covered through the National Health Fund when accessed via referral pathways, waiting times for neurological consultation and imaging can vary and may be prolonged in the public system. Advanced diagnostics, including genetic testing and biomarker analysis, are available but are not part of routine clinical practice and are often accessed privately or in research settings.

Diagnosis pathway

The diagnostic journey typically begins with a thorough medical history examination by the general practitioner, neurological examination, and cognitive testing (e.g., Mini-Mental State Examination (MMSE) or similar tools), as outlined by neurologists in Poland. These are used to assess memory, orientation, language, and other cognitive domains. Polish clinicians follow European and international dementia diagnostic recommendations. These include structured cognitive testing, selective use of neuroimaging and differential diagnostics, and careful exclusion of non‑AD causes.

Wait times

Short wait time (expected)

In Poland, the average waiting time for urgent neurology referrals is approximately 25 days, while for non-urgent (stable) cases, there are about 262,000–278,000 individuals currently on waiting lists, though specific waiting times are not reported. The average wait for outpatient neurology appointments increased from 27 to 30 days year-on-year, an 11% rise.

Diagnosis cost

Mostly or fully covered

Under Poland’s National Health Fund (NFZ), the core dementia diagnostic process is fully covered when accessed through the public referral pathway. This includes specialist consultations (neurology or psychiatry), neuropsychological testing (e.g., MMSE, MoCA), brain MRI or CT, basic laboratory tests, and EEG when clinically indicated. Patients may still incur costs related to transport or prescription co-payments.

Under Poland’s public healthcare system, the National Health Fund (Narodowy Fundusz Zdrowia, NFZ) fully covers the core dementia diagnostic pathway, provided patients follow the official referral system and remain within the public care network. This typically includes:

● Consultations with a neurologist or psychiatrist
● Neuropsychological assessments (e.g. MMSE, MoCA)
● Brain imaging (MRI or CT)
● Basic laboratory tests (including thyroid function, vitamin B12, blood count, and metabolic panel)
● Electroencephalography (EEG) where clinically indicated

For patients, these services are generally provided at no direct cost (0 PLN), aside from minor expenses such as travel or standard prescription co-payments.
By contrast, advanced diagnostic tools, such as biomarker testing and genetic analysis, are not routinely covered within the public system. This includes cerebrospinal fluid (CSF) biomarkers, PET imaging, and genetic tests (e.g. APOE genotyping or broader sequencing panels). Access to these services is therefore typically limited to private providers or research settings. As a result, patients who pursue these tests usually pay out of pocket, with costs ranging from several hundred złotych for basic genetic risk tests to over 10,000 złotych for comprehensive private diagnostic packages, particularly those that include PET imaging.

Cognitive tests

Available

The MMSE is one of the most widely used screening tools for dementia globally and in Poland. The Polish adaptation is frequently employed due to its reliability, ease of use, and availability. The Rowland Universal Dementia Assessment Scale (RUDAS) is also adapted for the Polish language and is considered to have advantage over MMSE due to the latter’s limited sensitivity, particularly in assessing executive functions. The adapted Montreal Cognitive Assessment (MoCA) (including MoCA 7.2 version) is one of the most available tests in Poland and it has been shown to outperform MMSE in identifying mild cognitive deficits.

Imaging tests

Commonly used

MRI and CT scans are widely used in routine clinical practice in Poland to support the diagnosis of Alzheimer’s disease (AD) and other dementias. However, access to diagnostic imaging for conditions like Alzheimer’s disease and related dementias is challenged by significant delays, especially in the public healthcare system. Waiting times for MRI, CT, and PET-CT scans vary considerably depending on the region and the urgency of the referral.

For MRI scans, patients can expect an average national wait time of around 80 days for the scan itself, followed by an additional 27 days for the radiology report. More recent data (January 2025) shows some improvement, with the national average MRI wait time reduced to approximately 58 days.

PET imaging, including amyloid PET (detecting amyloid-β plaques) and tau PET (visualizing tau tangles), is even more constrained in clinical use. While PET/CT infrastructure exists in Poland and is expanding, access is strongly shaped by National Health Fund (Narodowy Fundusz Zdrowia, NFZ) reimbursement policies, which limit the number and indications of publicly funded scans. Importantly, PET imaging is primarily reimbursed for oncological indications, and only covered when strict criteria are met; otherwise, patients must pay out of pocket.

Genetic tests

Genetic testing for Alzheimer’s disease is not part of routine care for most patients. However, two main types of tests are available in private clinics: APOE genotyping and next-generation sequencing (NGS) panels for early-onset or familial Alzheimer’s disease.

Both APOE genotyping and broad NGS panels are technically available in Poland, their use is limited and mostly concentrated in high-risk, early-onset, or research contexts. For the average patient with late-onset Alzheimer’s, genetic testing is usually self-funded if pursued at all.

Biomarker tests

Rarely used

CSF and PET biomarker tools, specifically cerebrospinal fluid (CSF) biomarkers and positron emission tomography (PET) imaging, are underutilised across healthcare systems, including Poland, largely due to cost, infrastructure requirements, and limited availability. CSF biomarker testing involves the analysis of amyloid beta 1-42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid obtained via lumbar puncture. Although this method is recognised as one of the most diagnostically valuable tools for confirming Alzheimer’s pathology, its use in Poland is largely confined to specialist neurology clinics and research settings. In routine practice, diagnosis still relies primarily on cognitive testing and structural imaging, with CSF testing used selectively, partly because it is invasive and not systematically embedded in standard diagnostic pathways.

Cognitive Tests

Available

The MMSE is one of the most widely used screening tools for dementia globally and in Poland. The Polish adaptation is frequently employed due to its reliability, ease of use, and availability. The Rowland Universal Dementia Assessment Scale (RUDAS) is also adapted for the Polish language and is considered to have advantage over MMSE due to the latter’s limited sensitivity, particularly in assessing executive functions. The adapted Montreal Cognitive Assessment (MoCA) (including MoCA 7.2 version) is one of the most available tests in Poland and it has been shown to outperform MMSE in identifying mild cognitive deficits.

Imaging Tests

Commonly used

MRI and CT scans are widely used in routine clinical practice in Poland to support the diagnosis of Alzheimer’s disease (AD) and other dementias. However, access to diagnostic imaging for conditions like Alzheimer’s disease and related dementias is challenged by significant delays, especially in the public healthcare system. Waiting times for MRI, CT, and PET-CT scans vary considerably depending on the region and the urgency of the referral.

For MRI scans, patients can expect an average national wait time of around 80 days for the scan itself, followed by an additional 27 days for the radiology report. More recent data (January 2025) shows some improvement, with the national average MRI wait time reduced to approximately 58 days.

PET imaging, including amyloid PET (detecting amyloid-β plaques) and tau PET (visualizing tau tangles), is even more constrained in clinical use. While PET/CT infrastructure exists in Poland and is expanding, access is strongly shaped by National Health Fund (Narodowy Fundusz Zdrowia, NFZ) reimbursement policies, which limit the number and indications of publicly funded scans. Importantly, PET imaging is primarily reimbursed for oncological indications, and only covered when strict criteria are met; otherwise, patients must pay out of pocket.

Genetic Tests

Genetic testing for Alzheimer’s disease is not part of routine care for most patients. However, two main types of tests are available in private clinics: APOE genotyping and next-generation sequencing (NGS) panels for early-onset or familial Alzheimer’s disease.

Both APOE genotyping and broad NGS panels are technically available in Poland, their use is limited and mostly concentrated in high-risk, early-onset, or research contexts. For the average patient with late-onset Alzheimer’s, genetic testing is usually self-funded if pursued at all.

Biomarker Tests

Rarely used

CSF and PET biomarker tools, specifically cerebrospinal fluid (CSF) biomarkers and positron emission tomography (PET) imaging, are underutilised across healthcare systems, including Poland, largely due to cost, infrastructure requirements, and limited availability. CSF biomarker testing involves the analysis of amyloid beta 1-42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid obtained via lumbar puncture. Although this method is recognised as one of the most diagnostically valuable tools for confirming Alzheimer’s pathology, its use in Poland is largely confined to specialist neurology clinics and research settings. In routine practice, diagnosis still relies primarily on cognitive testing and structural imaging, with CSF testing used selectively, partly because it is invasive and not systematically embedded in standard diagnostic pathways.

Treatment & Care

In Poland, specialised dementia care is available mainly in selected hospitals and rehabilitation centres, while dedicated Alzheimer’s clinics remain limited. Standard Alzheimer’s medications (donepezil, rivastigmine, galantamine, memantine) are available, and newer therapies may be accessed only in specialised centres. Families often bear part of the care costs: private care facilities typically cost around 2,500-8,000 PLN per month, while residents in state homes contribute up to 70% of their income. Financial support exists through caregiver allowances and social services, and some local programmes provide subsidised home-care visits, day-care centres, and caregiver guidance.

Specialized facilities and services

Fully dedicated Alzheimer’s clinics remain limited in Poland, but several centres provide specialised dementia care. These include the University Hospital in Kraków (multidisciplinary neurology services), John Paul II Western Hospital in Grodzisk Mazowiecki (Alzheimer’s diagnostic work-up), and the Constance Care Rehabilitation Centre (neurological and neuropsychological rehabilitation).

While fully dedicated Alzheimer’s clinics are still rare, several regional centres and hospital departments offer advanced diagnostic and care services tailored to dementia.

University Hospital in Kraków (Szpital Uniwersytecki w Krakowie) is a leading tertiary and academic centre with a specialised neurology department and multidisciplinary teams (neurologists, psychiatrists, neuropsychologists). It offers comprehensive dementia diagnostics, including cognitive testing and advanced imaging (MRI/CT), and plays a key role in complex cases and research-linked care.

John Paul II Western Hospital, Grodzisk Mazowiecki is a modern regional hospital near Warsaw providing standard dementia diagnostic work-ups, including neurological consultations, imaging, and cognitive assessments. It functions as an accessible referral centre within the public system.

Constance Care Rehabilitation Centre (Konstancin Care) is a private, multidisciplinary facility focused on neurorehabilitation and cognitive therapy, particularly for patients in moderate to advanced stages. It provides longer-term support through physiotherapy, neuropsychology, and functional rehabilitation, typically on a private-pay basis.

Approved medication

Generic Name Trade Name Used for
Donepezil Aricept, Aricept ODT, Adlarity, Eranz, Memac, Alzepil, Davia, Donecept, Donep, Donepex, Donesyn, Dopezil, Yasnal, Memorit, Pezale, Redumas, Zolpezil, Namzaric* Donepezil is indicated for the symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Official National Product Information
Rivastigmine Exelon, Exelon Patch, Prometax, Rivastach, Nimvastid Symptomatic treatment of mild to moderately severe Alzheimer’s dementia.
Symptomatic treatment of mild to moderately severe dementia in patients with idiopathic Parkinson’s disease.
Official National Product Information
Galantamine Razadyne, Razadyne ER, Reminyl, Reminyl XL, Nivalin, Lycoremine, Galsya Galantamine is indicated for the symptomatic treatment of mild to moderately severe dementia of the Alzheimer type.
Official National Product Information
Memantine Namenda, Namenda XR, Ebixa, Memary, Axura, Akatinol, Maruxa, Nemdatine, Namzaric* Treatment of adult patients with moderate to severe Alzheimer’s disease.
Official National Product Information
Lecanemab Leqembi Lecanemab is indicated for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease in adult patients that are apolipoprotein E ε4 (ApoE ε4) heterozygotes or non-carriers.
Official National Product Information
Donanemab Kisunla Donanemab is indicated for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease (AD) in adult patients that are apolipoprotein Eε4 (ApoE ε4) heterozygotes or non-carriers.
Official National Product Information

*Namzaric = combination of Donepezil and Memantine

Treatment cost

The total annual societal cost of dementia in Poland is estimated at over 11 billion PLN, roughly split between direct care expenses (medications, hygiene products, services) and indirect costs from caregiver productivity loss. Families typically spend between 1,000-2,500 PLN per quarter on out-of-pocket expenses.

Private care facilities cost approximately 2,500-8,000 PLN per month, depending on standard and room type. In state-run homes, residents contribute up to 70% of their income, with remaining costs covered by family or local authorities. Financial support measures include caregiver allowances and selected tax deductions for care-related expenses.

The total annual cost, including direct medical and non-medical expenses, as well as indirect costs like lost productivity, is estimated at over 11 billion PLN. Of this, around 5.4 billion PLN is spent on care, medications, and hygiene products. While another 5.7 billion PLN reflects economic losses from caregivers reducing or stopping work.

Family direct costs range from 1,000 PLN to over 2,500 PLN per three months to cover medications, hygiene supplies, and private medical visits. In many cases, this represents a third of a typical pension.

Monthly fees in private care facilities range from 2,500 PLN (for shared rooms) up to 8,000 PLN or more (for single rooms in high-standard facilities).

In state-run homes, residents pay up to 70% of their income, while the remainder is covered by family or local authorities. Average costs are typically 2,500–3,000 PLN/month.

Families may access several aid programs including care allowance for informal caregivers is around 2,988 PLN/month and allowance for non-working caregivers as well as tax reliefs: Health equipment, home adaptations, and care services may qualify as deductions.

Caregiver support

Caregivers in Poland have access to informational resources, including guides published by the National Health Fund and the Polish Alzheimer’s Society. Financial support includes a care allowance (approx. 2,988 PLN/month for eligible full-time caregivers), a smaller nursing allowance (approx. 215 PLN/month), and selected tax deductions for care-related expenses.

Local social services may provide subsidised home-care visits, while day-care centres and senior clubs offer respite and social activities for people in early to mid-stage dementia. Psychological support is available through national and regional dementia helplines.

In Poland, caregivers of people with Alzheimer’s disease have access to a combination of informational, financial, and legal support. A key educational resource is the guide “Poradnik dla opiekunów osób chorych na Alzheimera,” published jointly by the NZF and the Polish Alzheimer’s Society, which provides practical guidance on disease progression, daily care routines, legal issues, and psychological support. In parallel, the government offers several forms of financial assistance: the świadczenie pielęgnacyjne (care allowance), currently around 2,988 PLN per month, is available to individuals who leave employment to provide full-time care; the zasiłek pielęgnacyjny, approximately 215.84 PLN per month, offers more general support; and the specjalny zasiłek opiekuńczy is targeted at certain informal caregivers outside formal employment. Additional support is available through rehabilitation tax relief, which allows deductions for expenses related to care services, assistive devices, and medical equipment, helping to offset the broader financial burden of long-term dementia care.

Moreover, local social services can arrange for home visits by care workers handling tasks like medication reminders, shopping, and light household chores, often with partial or full financial subsidy depending on income.

Day Care Centers (“Dom Dzienny Pobytu”) and Senior Clubs are often volunteer-run or social-service-linked places provide engaging activities, like singing, reading aloud, group games, or walks, for people in early to mid-stages of AD. Caregivers benefit from a few respite hours. In general, multiple Alzheimer’s or dementia-focused hotlines exist across Poland, offering free emotional support, counselling, and guidance to caregivers.

Policy

Poland does not yet have a formal national dementia strategy, although the Ministry of Health has drafted the National Program of Actions against Dementia (2025-2030). Evidence highlights several system gaps: dementia remains underdiagnosed, with one study finding 72% of cases previously undetected, and treatment coverage is limited, with only about one-third of diagnosed patients receiving cognitive enhancers. Care is largely family-based, with around 92% of people with dementia cared for at home, while many caregivers report limited financial, informational, and respite support.

National dementia plan

Poland currently does not yet have a standing national dementia strategy, but is taking concrete steps to establish one, the first of its kind, aimed to be implemented between 2025 and 2030.

Upcoming plans

Poland’s Ministry of Health has drafted the National Program of Actions against Dementia (2025-2030), currently in final consultations and expected to be adopted in 2025. The program aims to strengthen and systematise dementia support, introduce coordinated systemic solutions, improve inter-ministerial collaboration, and enhance quality of life for people with dementia and their caregivers.

The Ministry of Health has drafted the “Krajowy Program Działań wobec Chorób Otępiennych na lata 2025–2030” (National Program of Actions against Dementia for 2025–2030). This plan is in the stage of final inter-ministerial consultations and is expected to be officially adopted—most likely in 2025.

The program’s key objectives include:

– Systematizing and expanding existing support for people with dementia and their caregivers
– Developing new, systemic solutions within available funding frameworks
– Enhancing inter-ministerial collaboration and engagement with civil society
– Improving the quality of life for patients and support for caregivers.

Policy gaps

Legal barriers

– Lack of a fully implemented national policy

– Underdiagnosis and Late Diagnosis
In a Polish geriatric ward study, 72% of dementia cases were not previously detected, highlighting a real gap in early diagnosis and systematic cognitive assessment in primary care.

– Fragmented and Hospital-Centric Care
A geriatric study revealed high undertreatment of diagnosed cases—only one-third of patients received cognitive enhancers. This points to fragmented care and discontinuity even after diagnosis.

– Limited Support for Informal Caregivers
A study found that 92% of elderly dementia patients in Poland are cared for at home, and 44% of caregivers have no external support.

– Policy Gaps Around Caregiver Respite and Support
EuroFAMCARE data highlight a “support gap” for Polish family caregivers—particularly in informational, organisational, and financial support, as well as respite care.

Cultural barriers

Deep-rooted cultural norms and social perceptions continue to shape how dementia is understood, diagnosed, and addressed across the country. One major obstacle is the strong tradition of family-based elder care. In Polish society, caring for older relatives is widely viewed as a moral duty and central to family identity. As Alzheimer Europe reports, this expectation often discourages families from seeking formal assistance or institutional support, with many relying instead on unpaid female caregivers at home.

Research

Alzheimer’s research in Poland is carried out mainly at universities and scientific institutes in major cities such as Warsaw, Poznań, and Wrocław. The country also participates in international clinical trials testing new Alzheimer’s treatments. Some studies focus on improving support for caregivers, including programs combining education and financial assistance.

Selected academic institutions

Nencki Institute of Experimental Biology (Polish Academy of Sciences), Warsaw The centre in neurobiology and biochemistry, the Nencki Institute houses the Neurobiology Center and departments focused on neurophysiology, molecular and cellular neurobiology. Research includes neurodegeneration, neuronal plasticity, and disease signalling pathways—all highly relevant to Alzheimer’s pathology. Laboratory of Neurodegeneration – International Institute of Molecular and Cell Biology (IIMCB), Warsaw This lab focuses on molecular degeneration processes in neurodegenerative diseases, including AD, using cell and animal models to uncover pathological mechanisms. Department of Neurodegenerative Disorders – Polish-Japanese Academy of Information Technology / Medical Research Centre (PAS), Warsaw The department integrates clinical and molecular research in AD, MCI, FTD, LBD, and vascular dementia. It includes an Alzheimer’s disease division in the Neurology Clinic and a neurogenetics laboratory, making it one of Poland's most extensive neurodegeneration research hubs. Wrocław University of Science and Technology & Nencki Institute Collaboration A recent project funded with nearly PLN 5 million involves designing antibody-drug conjugates targeting amyloid and tau, in partnership with the Nencki Institute. This puts Wrocław University on the front lines of therapeutic innovation for AD. Adam Mickiewicz University & Poznań University of Technology (Poznań) Together, they are developing an innovative early-detection method for Alzheimer’s called the Alzheimer Prediction Project, reflecting active pursuit of diagnostic breakthroughs.

Clinical trials and registries

In Poland, clinical trials are regulated and authorised by the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products (URPL) in cooperation with the Bioethics Committees, while approved studies are recorded at the European level in the EU Clinical Trials Information System (CTIS).

Selected innovative methods

Psychoeducational and financial intervention study: A recent study in Poland showed that caregivers who received both training in coping strategies and a modest stipend experienced significantly lower levels of depression and burden than those without support.

Support

Organizations are listed for informational purposes based on publicly available sources. Inclusion does not necessarily indicate affiliation with or endorsement by Alzheimer’s Disease International (ADI).

Support for people with Alzheimer’s disease and their families in Poland is provided mainly through foundations, patient organisations, and public awareness initiatives. These groups offer caregiver education, memory screening, specialist consultations, helplines, and advocacy, while also promoting public awareness and reducing stigma. National and regional organisations coordinate support services, information resources, and community initiatives for patients and caregivers.

Selected national associations, patient family associations, NGOs:

Selected initiatives

“Razem przed siebie” (“Forward with Dementia”) – Public awareness campaign (2021-2022) in Lower Silesia, part of the international COGNISANCE project, aimed at reducing stigma and increasing understanding of dementia.

Global ADI Conference (2024) – Poland hosted the 36th Alzheimer’s Disease International Conference in Kraków, bringing together researchers, clinicians, caregivers, and people living with dementia.

"Razem przed siebie” (“Forward with Dementia”) Awareness Campaign
"Razem przed siebie” (“Forward with Dementia”) Awareness Campaign was part of the international COGNISANCE project, co-designed by people with dementia, carers, healthcare professionals, and researchers.
It ran from September 2021 to April 2022, largely in Wrocław and Lower Silesia, with the goal of raising public awareness and reducing stigma around dementia.

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Global Conference of Alzheimer’s Disease International in Kraków
Poland, through the Polish Alzheimer Society, hosted the 36th Global Conference of Alzheimer’s Disease International in Kraków (April 2024), bringing together experts, caregivers, researchers, and people living with dementia.

Dedicated media outlets

In Poland, Alzheimer’s disease is covered through a combination of specialised health portals, organisational platforms, and broader media outlets. The medical website Medforum.pl features a dedicated “Choroba Alzheimera” section with regularly updated articles on research developments, risk factors, prevention strategies, and caregiving guidance, making it a key source of accessible, expert-informed content. At the organisational level, Alzheimer Polska, a national federation of Alzheimer’s associations, maintains an active news section publishing updates on advocacy efforts, legal developments, public awareness campaigns, and support resources for both caregivers and professionals. Similarly, the Polskie Stowarzyszenie Pomocy Osobom z Chorobą Alzheimera shares information on conferences, policy initiatives, and awareness activities, contributing to the visibility of dementia-related issues.

Understanding the terms

This section explains key terms used throughout the text to help readers better understand the exploration concepts.
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Contents

Understanding the Terms

Terms used throughout this website are explained below.
A

Amyloid-Targeting Therapies (ATT): A class of disease-modifying treatments, primarily monoclonal antibodies, designed to identify and remove amyloid-beta plaques from the brain to slow cognitive and functional decline in early-stage Alzheimer’s. Examples include Lecanemab and Donanemab.

Aphasia: A language disorder that affects a person’s ability to communicate, often seen early in Frontotemporal Dementia.

APOE ε4 Allele: A genetic variant of the Apolipoprotein E gene that is a major risk factor for late-onset Alzheimer’s disease; while not a causative gene, its presence increases the likelihood of developing the condition.

Acetylcholinesterase Inhibitors: A class of medications, including Donepezil, Rivastigmine, and Galantamine, used to treat cognitive symptoms by increasing levels of chemical messengers in the brain.

Advance Directives (DAT): Legal documents, such as Disposizioni Anticipate di Trattamento in Italy, that allow individuals to specify their future medical treatment and care preferences while they still have the capacity to do so.

Alzheimer’s Disease (AD): The most common cause of dementia, characterized by a progressive neurodegenerative decline caused by the accumulation of amyloid plaques and tau tangles in the brain.

Amyloid-beta Plaques: Protein fragments that build up in the spaces between nerve cells, disrupting communication and triggering immune responses.

Amyloid PET Scan: A specialized nuclear imaging test that uses radioactive tracers to visualize and measure the density of amyloid-beta plaques in the living brain.

Atrophy: The wasting away or shrinking of brain tissue, often measured via MRI to support a clinical diagnosis of dementia or Alzheimer’s.

B

Biomarkers: Measurable biological indicators, such as proteins found in blood or cerebrospinal fluid, used to identify the underlying pathology of a disease.

Blood Biomarkers: Emerging, less-invasive diagnostic tests that measure specific proteins like p-tau or neurofilament levels in blood plasma to detect Alzheimer’s pathology.

C

CSF Analysis (Cerebrospinal Fluid): A diagnostic procedure involving a lumbar puncture to measure levels of tau and amyloid-beta proteins in the fluid surrounding the brain and spinal cord.

CT Scan (Computed Tomography): A diagnostic imaging test using X-rays to create detailed cross-sectional images of the brain; used primarily to rule out other causes of cognitive decline such as tumors or strokes.

Clock Drawing Test (CDT): A brief cognitive screening task where a patient is asked to ask to draw a clock face; it evaluates visuospatial and executive function.

Cognitive Screening: The process of using standardized tests to objectively measure an individual’s mental functions, such as memory, orientation, and attention.

Community-based Care: Healthcare and support services provided within the local community, such as daycare centers, home-based nursing, and local support groups, rather than in institutional settings.

Cube Copying Test: A visuospatial assessment task used during neuropsychological evaluations to test a patient’s ability to replicate geometric shapes.

D

Dementia: An umbrella term for a range of neurological conditions characterized by a decline in memory, language, and thinking skills severe enough to interfere with daily life.

Dementia-friendly Society: A community or national environment where citizens and businesses are trained to understand, respect, and support the needs of people living with dementia.

Disease-modifying Therapies (DMTs): A new class of treatments, such as monoclonal antibodies (e.g., Lecanemab), designed to target the underlying biological causes of Alzheimer’s rather than just managing symptoms.

E

Early-Onset Alzheimer’s: A form of the disease that affects people younger than age 65, often linked to the familial genes.

Executive Function: Higher-level mental skills including planning, focusing, and multitasking; these are often what the Clock Drawing Test evaluates.

F

FDG-PET: A type of PET scan that measures glucose metabolism in the brain to identify patterns characteristic of different dementia subtypes.

Familial Alzheimer’s Disease: A rare, genetic form of the disease linked to mutations in specific genes (APP, PSEN1, PSEN2) that typically presents with early-onset symptoms.

Frontotemporal Dementia (FTD): A type of dementia caused by progressive nerve cell loss in the frontal or temporal lobes, leading to significant changes in behavior, personality, and language.

G

General Practitioner (GP): A primary care physician who acts as the first point of contact and gatekeeper for dementia diagnosis, providing initial assessments and referrals to specialists.

Genotyping: The analysis of an individual’s DNA to identify specific genetic variations associated with dementia risk or causation.

H

Hidden Cost: The indirect economic impacts of dementia, such as the loss of income for family members who must reduce working hours or leave their jobs to provide care.

I

Informal Care / Informal Caregiver: Unpaid care provided by family members, spouses, or friends, which represents the vast majority of long-term support for people living with dementia.

J

Japanese Cognitive Function Test (J-Cog): A specialized cognitive assessment tool used to evaluate mental and functional status in specific research or regional contexts.

L

Lewy Body Dementia (LBD): A type of progressive dementia that leads to a decline in thinking, reasoning, and independent function due to abnormal microscopic deposits that damage brain cells.

Long-Term Care Insurance (LTCI): A specialized branch of insurance, found in systems like Germany and Singapore, that provides financial subsidies for daily living assistance and nursing care.

M

Memory Clinic: A specialized, often multidisciplinary center focused on the expert diagnosis, management, and treatment of dementia and cognitive disorders.

Mild Cognitive Impairment (MCI): An intermediate stage between normal aging and dementia where memory or thinking problems are noticeable but don’t yet prevent daily functioning.

Mini-Mental State Examination (MMSE): A 30-point standardized questionnaire used to measure cognitive impairment by testing orientation, recall, and attention.

Montreal Cognitive Assessment (MoCA): A cognitive screening tool designed to be more sensitive than the MMSE, particularly for identifying Mild Cognitive Impairment.

MRI Scan (Magnetic Resonance Imaging): A non-invasive technology using magnetic fields to produce detailed images of brain structure; used to assess brain atrophy and rule out secondary causes.

N

National Dementia Plan: A formal government strategy outlining a coordinated response to manage dementia diagnosis, care, research, and awareness at a national level.

National Health Insurance (NHI): A government-funded or regulated healthcare system providing universal or subsidized medical services to citizens.

Neuroimaging: The use of advanced techniques, such as CT, MRI, and PET, to visualize the structure and function of the brain for diagnostic purposes.

Neuroinflammation: The brain’s immune response to damage or protein buildup; while initially protective, chronic inflammation can accelerate neurodegeneration.

O

Out-of-Pocket Costs: Direct payments made by patients or their families for medical services, tests, or care that are not covered by insurance or public subsidies.

P

Preclinical Alzheimer’s: The stage where brain changes (like amyloid buildup) are present but no outward symptoms are yet visible.

S

Synaptic Loss: The destruction of synapses (the gaps where neurons communicate), which is often the strongest correlate to cognitive decline.

T

Tau Tangles: Twisted fibers of a protein called tau that build up inside nerve cells, destroying the cell’s transport system.

V

Vascular Dementia: The second most common type of dementia, caused by conditions that block or reduce blood flow to the brain, like strokes.